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Details

Stereochemistry ABSOLUTE
Molecular Formula C21H36O3
Molecular Weight 336.5087
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PREGNANE-3,17,20-TRIOL, (3.ALPHA.,5.BETA.,20S)-

SMILES

C[C@H](O)[C@@]1(O)CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

InChIKey=SCPADBBISMMJAW-UHHUKTEYSA-N
InChI=1S/C21H36O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h13-18,22-24H,4-12H2,1-3H3/t13-,14+,15+,16+,17-,18-,19-,20-,21-/m0/s1

HIDE SMILES / InChI

Description

Pregnanetriol is a steroid metabolite of progesterone. Elevated levels of pregnanetriol in urine indicate a disruption of adrenal steroidogenic pathways.

Originator

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Natural Metabolite
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Monitoring of therapy in congenital adrenal hyperplasia.
2010-08
Estimation of pregnanediol and pregnanetriol in urine.
1965-06
Patents

Patents

US 225526
1

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
A method for determination of pregnanetriol in the urine of patients consists of enzymatic hydrolysis, extraction, and purification, thin-layer chromatography, and quantitation by the color reaction.
Name Type Language
PREGNANE-3,17,20-TRIOL, (3.ALPHA.,5.BETA.,20S)-
Systematic Name English
NSC-52760
Preferred Name English
3.ALPHA.,17.ALPHA.,20.ALPHA.-TRIHYDROXY-5.BETA.-PREGNANE
Common Name English
5.BETA.-PREGNANE-3.ALPHA.,17.ALPHA.,20.ALPHA.-TRIOL
Common Name English
5.BETA.-PREGNANE-3.ALPHA.,17,20.ALPHA.-TRIOL
Common Name English
PREGNANETRIOL
Systematic Name English
Classification Tree Code System Code
LOINC 39566-5
Created by admin on Mon Mar 31 21:33:22 GMT 2025 , Edited by admin on Mon Mar 31 21:33:22 GMT 2025
LOINC 82899-6
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LOINC 82852-5
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LOINC 34361-6
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LOINC 82853-3
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LOINC 34360-8
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LOINC 82855-8
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LOINC 15092-0
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LOINC 2836-5
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LOINC 14886-6
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LOINC 82854-1
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LOINC 2835-7
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LOINC 30512-8
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LOINC 82898-8
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CFR 21 CFR 862.1610
Created by admin on Mon Mar 31 21:33:22 GMT 2025 , Edited by admin on Mon Mar 31 21:33:22 GMT 2025
Code System Code Type Description
EPA CompTox
DTXSID00911364
Created by admin on Mon Mar 31 21:33:22 GMT 2025 , Edited by admin on Mon Mar 31 21:33:22 GMT 2025
PRIMARY
NSC
52760
Created by admin on Mon Mar 31 21:33:22 GMT 2025 , Edited by admin on Mon Mar 31 21:33:22 GMT 2025
PRIMARY
PUBCHEM
101967
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PRIMARY
ECHA (EC/EINECS)
214-148-0
Created by admin on Mon Mar 31 21:33:22 GMT 2025 , Edited by admin on Mon Mar 31 21:33:22 GMT 2025
PRIMARY
CAS
1098-45-9
Created by admin on Mon Mar 31 21:33:22 GMT 2025 , Edited by admin on Mon Mar 31 21:33:22 GMT 2025
PRIMARY
FDA UNII
43822S61TB
Created by admin on Mon Mar 31 21:33:22 GMT 2025 , Edited by admin on Mon Mar 31 21:33:22 GMT 2025
PRIMARY
WIKIPEDIA
PREGNANETRIOL
Created by admin on Mon Mar 31 21:33:22 GMT 2025 , Edited by admin on Mon Mar 31 21:33:22 GMT 2025
PRIMARY
NIH
NCATS
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