METUREDEPA

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H22N3O3P
Molecular Weight	275.2844
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)NP(=O)(N1CC1(C)C)N2CC2(C)C

InChI

InChIKey=QTFKTBRIGWJQQL-UHFFFAOYSA-N

InChI=1S/C11H22N3O3P/c1-6-17-9(15)12-18(16,13-7-10(13,2)3)14-8-11(14,4)5/h6-8H2,1-5H3,(H,12,15,16)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4895430 | https://www.ncbi.nlm.nih.gov/pubmed/13918060

Meturedepa (also known as AB-132), an alkylating agent that was developed as an antineoplastic drug. Meturedepa was studied to treat lymphomas and leukemias. The drug also participated in the Eastern clinical drug evaluation program for 233 patients with advanced cancer. Information about the current use of this compound is not available.

Approval Year

PubMed

Title	Date	PubMed
Clinical experience with a new alkylating agent AB-132, in the treatment of lymphomas and leukemias.	1962 May	13918060
Prolonged apnea following succinylcholine in cancer patients receiving AB-132.	1963 May-Jun	13998795
COMBINED USE OF AB-132 (METUREDEPA, TURLOC) AND X-IRRADIATION IN THE MANAGEMENT OF ADVANCED BRONCHOGENIC CARCINOMA.	1964 Jul	14184043
Effects of meturedepa (NSC-51325) in 233 patients with advanced cancer. Eastern Clinical Drug Evaluation Program.	1968 Oct	4895430

Name

Type

Language

METUREDEPA

Official Name

English

Ethyl [bis(2,2-dimethyl-1-aziridinyl)phosphinyl]carbamate

Systematic Name

English

meturedepa [INN]

Common Name

English

METUREDEPA [USAN]

Common Name

English

AB-132

Code

English

CARBAMIC ACID, (BIS(2,2-DIMETHYL-1-AZIRIDINYL)PHOSPHINYL)-, ETHYL ESTER

Common Name

English

NSC-51325

Code

English

METUREDEPA [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C292