GUVACINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H9NO2
Molecular Weight	127.1412
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

OC(=O)C1=CCCNC1

InChI

InChIKey=QTDZOWFRBNTPQR-UHFFFAOYSA-N

InChI=1S/C6H9NO2/c8-6(9)5-2-1-3-7-4-5/h2,7H,1,3-4H2,(H,8,9)

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Potency
GABA transporter 1 8	Inhibitor 8,297	14.0 µM [IC50]
GABA transporter 3 6	Inhibitor 8,297	119.0 µM [IC50]
Betaine transporter 4	Inhibitor 8,297	1870.0 µM [IC50]
GABA transporter 2 3	Inhibitor 8,297	66.0 µM [IC50]

PubMed

PubMed

Show entries

Title	Date	PubMed
Gamma-aminobutyric acid transporter (BGT-1) expressed in human astrocytoma U373 MG cells: pharmacological and molecular characterization and phorbol ester-induced inhibition.	2002 Jul 1	12111824
Effects of 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazol (exo-THPO) and its N-substituted analogs on GABA transport in cultured neurons and astrocytes and by the four cloned mouse GABA transporters.	2003 Sep-Oct	12742090

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Name

Type

Language

GUVACINE

Common Name

English

GUVACINE [MI]

Common Name

English

1,2,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLIC ACID

Systematic Name

English

1,2,5,6-TETRAHYDRONICOTINIC ACID

Systematic Name

English

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Code System

Code

Type

Description

WIKIPEDIA

GUVACINE

PRIMARY

FDA UNII

41538P325K

PRIMARY

MESH

C015910

PRIMARY

PUBCHEM

3532

PRIMARY

DRUG BANK

DB08848

PRIMARY

Showing 1 to 5 of 9 entries

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SUBSTANCE RECORD


					41538P325K

GUVACINE