GUVACINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H9NO2
Molecular Weight	127.1412
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

OC(=O)C1=CCCNC1

InChI

InChIKey=QTDZOWFRBNTPQR-UHFFFAOYSA-N

InChI=1S/C6H9NO2/c8-6(9)5-2-1-3-7-4-5/h2,7H,1,3-4H2,(H,8,9)

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Potency
GABA transporter 1 11	Inhibitor 8,504	14.0 µM [IC50]
GABA transporter 3 7	Inhibitor 8,504	119.0 µM [IC50]
Betaine transporter 4	Inhibitor 8,504	1870.0 µM [IC50]
GABA transporter 2 4	Inhibitor 8,504	66.0 µM [IC50]

PubMed

PubMed

Show entries

Title	Date	PubMed
Betel nut chewing and subclinical ischemic heart disease in diabetic patients.	2010 Nov 4	21076525
Antiovulatory and abortifacient effects of Areca catechu (betel nut) in female rats.	2010 Oct	21206624
A possible role of the non-GAT1 GABA transporters in transfer of GABA from GABAergic to glutamatergic neurons in mouse cerebellar neuronal cultures.	2010 Sep	20512624

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Name

Type

Language

GUVACINE [MI]

Preferred Name

English

GUVACINE

Common Name

English

1,2,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLIC ACID

Systematic Name

English

1,2,5,6-TETRAHYDRONICOTINIC ACID

Systematic Name

English

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Code System

Code

Type

Description

WIKIPEDIA

GUVACINE

PRIMARY

FDA UNII

41538P325K

PRIMARY

MESH

C015910

PRIMARY

PUBCHEM

3532

PRIMARY

DRUG BANK

DB08848

PRIMARY

Showing 1 to 5 of 9 entries

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SUBSTANCE RECORD


					41538P325K

GUVACINE