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Details

Stereochemistry ACHIRAL
Molecular Formula C17H14N2O3
Molecular Weight 294.3047
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ROSOXACIN

SMILES

CCN1C=C(C(O)=O)C(=O)C2=CC=C(C=C12)C3=CC=NC=C3

InChI

InChIKey=XBPZXDSZHPDXQU-UHFFFAOYSA-N
InChI=1S/C17H14N2O3/c1-2-19-10-14(17(21)22)16(20)13-4-3-12(9-15(13)19)11-5-7-18-8-6-11/h3-10H,2H2,1H3,(H,21,22)

HIDE SMILES / InChI

Description

Rosoxacin, a quinolone derivative, is an antibiotic, which is used for the treatment of uncomplicated acute gonococcal urethritis. Administration of rosoxacin is an effective regimen for the therapy of chancroid and is a reasonable alternative to other short-course regimens. The drug binds to and inhibits two enzymes topoisomerase II (DNA gyrase), which is required for bacterial DNA replication, transcription, repair, and recombination.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
a single 300 mg capsule
Route of Administration: Oral