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Details

Stereochemistry ACHIRAL
Molecular Formula C34H34N4O4
Molecular Weight 562.6582
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of BILB-1941

SMILES

CN1C2=C(C=CC(=C2)C(=O)NC3(CCC3)C(=O)NC4=CC=C(\C=C\C(O)=O)C=C4)C(C5CCCC5)=C1C6=CC=CC=N6

InChI

InChIKey=JBSNALXXNTWUEC-SFQUDFHCSA-N
InChI=1S/C34H34N4O4/c1-38-28-21-24(13-16-26(28)30(23-7-2-3-8-23)31(38)27-9-4-5-20-35-27)32(41)37-34(18-6-19-34)33(42)36-25-14-10-22(11-15-25)12-17-29(39)40/h4-5,9-17,20-21,23H,2-3,6-8,18-19H2,1H3,(H,36,42)(H,37,41)(H,39,40)/b17-12+

HIDE SMILES / InChI

Approval Year

Name Type Language
BILB-1941
Common Name English
(2E)-3-(4-(((1-(((3-CYCLOPENTYL-1-METHYL-2-(2-PYRIDINYL)-1H-INDOL-6-YL)CARBONYL)AMINO)CYCLOBUTYL)CARBONYL)AMINO)PHENYL)-2-PROPENOIC ACID
Systematic Name English
N-(1-(((4-((E)-2-(CARBOXY)ETHENYL)PHENYL)AMINO)CARBONYL)CYCLOBUTYL)-3-CYCLOPENTYL-1-METHYL-2-(PYRIDIN-2-YL)INDOLE-6-CARBOXAMIDE
Systematic Name English
2-PROPENOIC ACID, 3-(4-(((1-(((3-CYCLOPENTYL-1-METHYL-2-(2-PYRIDINYL)-1H-INDOL-6-YL)CARBONYL)AMINO)CYCLOBUTYL)CARBONYL)AMINO)PHENYL)-, (2E)-
Systematic Name English
BILB-1941ZW
Code English
Code System Code Type Description
CAS
494856-61-0
Created by admin on Sat Dec 16 11:38:20 GMT 2023 , Edited by admin on Sat Dec 16 11:38:20 GMT 2023
PRIMARY
FDA UNII
3WV68DY85W
Created by admin on Sat Dec 16 11:38:20 GMT 2023 , Edited by admin on Sat Dec 16 11:38:20 GMT 2023
PRIMARY
PUBCHEM
56949326
Created by admin on Sat Dec 16 11:38:20 GMT 2023 , Edited by admin on Sat Dec 16 11:38:20 GMT 2023
PRIMARY
CLINICAL_TRIALS.GOV
BILB-1941
Created by admin on Sat Dec 16 11:38:20 GMT 2023 , Edited by admin on Sat Dec 16 11:38:20 GMT 2023
PRIMARY Official Title: A Multinational Randomised, Double-blind, Placebo Controlled Study to Evaluate the Antiviral Pharmacodynamic Effect, Safety, and Pharmacokinetics of Escalating Doses of BILB 1941 ZW Oral Solution Administered Q8H for Five Days to Patients With Chronic Hepatitis C Genotype 1 Virus Infection.Purpose: To assess the antiviral effect, safety and pharmacokinetics of rising doses of 10 mg, 20 mg, 40 mg, 60 mg, 80 mg, 100 mg, 150 mg, 200 mg, 300 mg, 450 mg, 650 mg, 900 mg oral BILB 1941 ZW administered Q8H in a polyethyleneglycol 400 (PEG 400): distilled water: Tromethamine (TRIS) drinking solution for five days to patients with chronic HCV genotype 1 infection.