CLORPRENALINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H16ClNO
Molecular Weight	213.704
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)NCC(O)C1=C(Cl)C=CC=C1

InChI

InChIKey=SSMSBSWKLKKXGG-UHFFFAOYSA-N

InChI=1S/C11H16ClNO/c1-8(2)13-7-11(14)9-5-3-4-6-10(9)12/h3-6,8,11,13-14H,7H2,1-2H3

HIDE SMILES / InChI

Description
Sources: http://www.chemicalbook.com/ChemicalProductProperty_EN_CB2291187.htm
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/25285506 | https://www.ncbi.nlm.nih.gov/pubmed/13376372

Clorprenaline is a β2-adrenergic receptor agonist. As a bronchodilator it has been used for the treatment of bronchial asthma, bronchitis and other respiratory diseases. It is a potential new lean meat-boosting feed additive because it can promote animal muscular mass growth and decrease fat accumulation.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Beta-2 adrenergic receptor 203 Target ID: CHEMBL210 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26002106 \| https://www.ncbi.nlm.nih.gov/pubmed/27859454	Agonist 2678

Conditions

Condition	Modality	Targets	Highest Phase	Product
Asthma 241 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14400681 https://www.ncbi.nlm.nih.gov/pubmed/13868694	Primary		Approved 8429	Unknown Approved Use Clorprenaline has been commonly used for the treatment of bronchial asthma, bronchitis and other respiratory diseases in clinical.

PubMed

Title	Date	PubMed
[Simultaneous determination of nine beta-agonist residues in animal derived foods by ultra performance liquid chromatography-tandem mass spectrometry].	2008 Nov	19253549
1-(2-Chloro-phen-yl)-2-(isopropyl-amino)ethanol.	2009 Jun 6	21582800

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Other

In Vitro Use Guide

Unknown

Name

Type

Language

CLORPRENALINE

Official Name

English

clorprenaline [INN]

Common Name

English

CLORPRENALINE [MI]

Common Name

English

ORTHO-CHLORO-.ALPHA.((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL

Systematic Name

English

BENZENEMETHANOL, 2-CHLORO-.ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)

Common Name

English

Clorprenaline [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C48149