Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C14H19NO2 |
Molecular Weight | 233.3062 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(CCCCN1)[C@H](OC(C)=O)C2=CC=CC=C2
InChI
InChIKey=BKPLVPRTTWIDNL-ZIAGYGMSSA-N
InChI=1S/C14H19NO2/c1-11(16)17-14(12-7-3-2-4-8-12)13-9-5-6-10-15-13/h2-4,7-8,13-15H,5-6,9-10H2,1H3/t13-,14-/m1/s1
Levophacetoperane is a piperidine derivative. Levofacetoperane is a sympathomimetic central nervous system stimulant and is commonly used to treat depression. Levophacetoperane is also a known analeptic and is strongly linked to apnea reversal in dogs after a single intravenous injection.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: GO:0051620 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29714 |
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Target ID: GO:0090494 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29714 |
PubMed
Title | Date | PubMed |
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[Clinical tests of the activity of RP 8228 (phacetoperane) in an oligophrenic child]. | 1960 |
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The stimulating effect of RP 8228 on inactive psychiatric patients. | 1961 Nov-Dec |
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[Clinical study of a new psychoactive drug in psychiatry, RP-8228 or threo-levo-1-phenyl-1-(2-piperidyl)-1-acetoxymethane HCl]. | 1962 Apr |
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[The present status of RP-8228 in psychiatric therapeutics. Apropos of 32 recent cases]. | 1962 Oct 28 |
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[Obesity in pregnancy. Trial of RP 8228. 1-Phenyl-1-(2-piperidyl)-1-acetoxymethane HCi. Threolevogyric form]. | 1963 Jan |
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[FOREIGN PSYCHOPHARMACOLOGICAL DRUGS: LEVOFACETOPERANE (8228 RP)]. | 1964 Oct 31 |
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Isolation and detection of methylphenidate, phacetoperane and some other sympatomimetic central nervous stimulants with special reference to doping. I. Gas chromatographic detection procedure with electron capture detection for some secondary amines. | 1975 Mar 26 |
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C47795
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m6791
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3319
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)