U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C6H14O
Molecular Weight 102.1748
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETHYL TERT-BUTYL ETHER

SMILES

CCOC(C)(C)C

InChI

InChIKey=NUMQCACRALPSHD-UHFFFAOYSA-N
InChI=1S/C6H14O/c1-5-7-6(2,3)4/h5H2,1-4H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Assessment of the reproductive toxicity of inhalation exposure to ethyl tertiary butyl ether in male mice with normal, low active and inactive ALDH2.
2014-04
Mode of action of ethyl tertiary-butyl ether hepatotumorigenicity in the rat: evidence for a role of oxidative stress via activation of CAR, PXR and PPAR signaling pathways.
2013-12-01
Subchronic exposure to ethyl tertiary butyl ether resulting in genetic damage in Aldh2 knockout mice.
2013-09-15
Craniofacial abnormalities and altered wnt and mmp mRNA expression in zebrafish embryos exposed to gasoline oxygenates ETBE and TAME.
2012-09-15
Differential genotoxic effects of subchronic exposure to ethyl tertiary butyl ether in the livers of Aldh2 knockout and wild-type mice.
2012-04
Medium-term multi-organ carcinogenesis bioassay of ethyl tertiary-butyl ether in rats.
2011-11-18
A one-generation reproductive toxicity study of ethyl tertiary butyl ether in rats.
2010-11
Urinary BTEX, MTBE and naphthalene as biomarkers to gain environmental exposure profiles of the general population.
2010-06-15
Ethyl t-butyl ether: review of reproductive and developmental toxicity.
2010-06
Cytochromes P450-mediated degradation of fuel oxygenates by environmental isolates.
2010-05
Ether oxygenate additives in gasoline reduce toxicity of exhausts.
2010-02-09
TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.
2010-01
Analysis of volatile organic compounds (VOCs) in the headspace of NCI-H1666 lung cancer cells.
2010
Effect of ETBE on reproductive steroids in male rats and rat Leydig cell cultures.
2009-10-08
Predicted roles of the uncharacterized clustered genes in aflatoxin biosynthesis.
2009-09
Inhibition of IgE-induced mast cell activation by ethyl tertiary-butyl ether, a bioethanol-derived fuel oxygenate.
2009-09
Inverse temperature dependence of Henry's law coefficients for volatile organic compounds in supercooled water.
2009-09
Odour and flavour thresholds of gasoline additives (MTBE, ETBE and TAME) and their occurrence in Dutch drinking water collection areas.
2009-07
Single-walled carbon nanotubes as an effective adsorbent in solid-phase microextraction of low level methyl tert-butyl ether, ethyl tert-butyl ether and methyl tert-amyl ether from human urine.
2009-05-15
Isotopic fractionation of methyl tert-butyl ether suggests different initial reaction mechanisms during aerobic biodegradation.
2009-04-15
Mineralization of methyl tert-butyl ether and other gasoline oxygenates by Pseudomonads using short n-alkanes as growth source.
2009-04
Direct screening of ground water samples for fuel oxygenates by headspace liquid phase microextraction-gas chromatography.
2008-12
Release of volatile organic compounds (VOCs) from the lung cancer cell line CALU-1 in vitro.
2008-11-24
Selection and identification of bacterial strains with methyl-tert-butyl ether, ethyl-tert-butyl ether, and tert-amyl methyl ether degrading capacities.
2008-11
Comparative genome analysis of filamentous fungi reveals gene family expansions associated with fungal pathogenesis.
2008-06-04
Measurement of fuel oxygenates in tap water using solid-phase microextraction gas chromatography-mass spectrometry.
2008-05-22
Degradation of fuel oxygenates and their main intermediates by Aquincola tertiaricarbonis L108.
2008-05
Quantification of fuel oxygenate ethers in human blood using solid-phase microextraction coupled with gas chromatography-high-resolution mass spectrometry.
2008-05
Study of fuel oxygenates solubility in aqueous media as a function of temperature and tert-butyl alcohol concentration.
2008-05
Simultaneous determination of gasoline oxygenates and benzene, toluene, ethylbenzene and xylene in water samples using headspace-programmed temperature vaporization-fast gas chromatography-mass spectrometry.
2007-12-14
Temperature effect on tert-butyl alcohol (TBA) biodegradation kinetics in hyporheic zone soils.
2007-09-19
Mono-, di-, and tri-tert-butyl ethers of glycerol. A molecular spectroscopic study.
2007-07
n-Alkane assimilation and tert-butyl alcohol (TBA) oxidation capacity in Mycobacterium austroafricanum strains.
2007-06
Ethyl tertiary-butyl ether: a toxicological review.
2007-05
Variations in 13C/12C and D/H enrichment factors of aerobic bacterial fuel oxygenate degradation.
2007-03-15
Effects of environmental settings on MTBE removal for a mixed culture and its monoculture isolation.
2007-02
Determination of low level methyl tert-butyl ether, ethyl tert-butyl ether and methyl tert-amyl ether in human urine by HS-SPME gas chromatography/mass spectrometry.
2007-01-02
Ozonation and combined ozone/H2O2, UV/ozone and UV/H2O2 for treatment of fuel oxygenates MTBE, ETBE, TAME, and DIPE from water--a comparison of removal efficiencies.
2007
Contributions of silane cross-linked PEX pipe to chemical/solvent odours in drinking water.
2007
Simultaneous determination of methyl tert-butyl ether, its degradation products and other gasoline additives in soil samples by closed-system purge-and-trap gas chromatography-mass spectrometry.
2006-11-03
Enzymes and genes involved in the aerobic biodegradation of methyl tert-butyl ether (MTBE).
2006-09
Isolation and characterization of a new Mycobacterium austroafricanum strain, IFP 2015, growing on MTBE.
2006-04
Experimental and theoretical studies on formation and degradation of chloro organic compounds.
2006-03
Air-water transfer of MTBE, its degradation products, and alternative fuel oxygenates: the role of temperature.
2004-10-15
Microbial degradation of methyl tert-butyl ether and tert-butyl alcohol in the subsurface.
2004-06
Determination of fuel dialkyl ethers and BTEX in water using headspace solid-phase microextraction and gas chromatography-flame ionization detection.
2004-04-16
Influence of oxygenated fuel additives and their metabolites on gamma-aminobutyric acidA (GABAA) receptor function in rat brain synaptoneurosomes.
2004-03-07
Avoiding hydrolysis of fuel ether oxygenates during static headspace analysis.
2003-11-01
Simultaneous determination of methyl tert.-butyl ether and its degradation products, other gasoline oxygenates and benzene, toluene, ethylbenzene and xylenes in Catalonian groundwater by purge-and-trap-gas chromatography-mass spectrometry.
2003-05-02
Growth enhancement of ETBE-degrading bacterial consortium with various carbon sources.
2003
Patents
Name Type Language
ETHYL TERT-BUTYL ETHER
MI  
Systematic Name English
NSC-1069
Preferred Name English
1,1-DIMETHYLETHYL ETHYL ETHER
Systematic Name English
METHYL-2-ETHOXYPROPANE, 2-
Systematic Name English
ETBE
Common Name English
ETHYL TERT-BUTYL ETHER [MI]
Common Name English
ETHYL TERT-BUTYL OXIDE
Systematic Name English
ETHYL 1,1-DIMETHYLETHYL ETHER
Systematic Name English
TERT-BUTYL ETHYL ETHER
Systematic Name English
2-ETHOXY-2-METHYLPROPANE
Systematic Name English
Code System Code Type Description
HSDB
7867
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
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NSC
1069
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
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MESH
C098546
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
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FDA UNII
3R9B16WR19
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
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ECHA (EC/EINECS)
211-309-7
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
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MERCK INDEX
m5099
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
PRIMARY Merck Index
CHEBI
141564
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
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EPA CompTox
DTXSID0025604
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
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PUBCHEM
12512
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
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CAS
637-92-3
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
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WIKIPEDIA
Ethyl tert-butyl ether
Created by admin on Mon Mar 31 19:01:15 GMT 2025 , Edited by admin on Mon Mar 31 19:01:15 GMT 2025
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