CAPOBENIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H23NO6
Molecular Weight	325.3569
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC(=CC(OC)=C1OC)C(=O)NCCCCCC(O)=O

InChI

InChIKey=MPTXLVRHYGBOQY-UHFFFAOYSA-N

InChI=1S/C16H23NO6/c1-21-12-9-11(10-13(22-2)15(12)23-3)16(20)17-8-6-4-5-7-14(18)19/h9-10H,4-8H2,1-3H3,(H,17,20)(H,18,19)

HIDE SMILES / InChI

Description
Sources: https://patents.google.com/patent/EP1955693A1 | https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA210&lpg=PA210&dq=Cardobiol retrieved from The Dictionary of Drugs: Chemical Data; Book Subtitle: Chemical Data, Structures and Bibliographies; Editors. J. Elks., p.210

Capobenic acid is an antiarrythmetic agent, vasodilator, antianginal used for the treatment of cardiac infarction.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Myocardial infarction 125 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4710126 https://www.ncbi.nlm.nih.gov/pubmed/1196538	Primary		Approved 8583	Cardobiol Approved Use Treatment of cardiac infarction

PubMed

Title	Date	PubMed
[Effect of 3,4,5-trimethoxy-benzoyl-aminocaproic acid on the cytolytic process in myocardial infarct. Working hypothesis].	1975-12-05	1196538
[Therapy of myocardial infarct with 3,4,5-trimethoxy-benzoyl-amino-caproic acid or C-3. Observations on 60 cases studied in an intensive coronary care unit].	1973-04	4710126

Patents

Sample Use Guides

In Vivo Use Guide

LD50 i.p. in rats: 2.5 g/kg

Route of Administration: Intraperitoneal

In Vitro Use Guide

Unknown

Name

Type

Language

CAPOBENIC ACID

Official Name

English

C-3

Preferred Name

English

6-(3,4,5-TRIMETHOXYBENZAMIDO)HEXANOIC ACID

Systematic Name

English

CAPOBENIC ACID [MART.]

Common Name

English

NSC-759126

Code

English

CAPOBENIC ACID [MI]

Common Name

English

CAPOBENIC ACID [USAN]

Common Name

English

NSC-230936

Code

English

HEXANOIC ACID, 6-((3,4,5-TRIMETHOXYBENZOYL)AMINO)-

Common Name

English

capobenic acid [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707