REMDESIVIR

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H35N6O8P
Molecular Weight	602.576
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of REMDESIVIR

Structure Search

SMILES

CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@H]1O[C@](C#N)([C@H](O)[C@@H]1O)C2=CC=C3N2N=CN=C3N)OC4=CC=CC=C4

InChI

InChIKey=RWWYLEGWBNMMLJ-YSOARWBDSA-N

InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

REMDESIVIR

Official Name

English

2-ETHYLBUTYL (2S)-2-(((2R, 3S, 4R, 5R)-5-(4-AMINOPYRROLO(2,1-F) (1,2,4)TRIAZIN-7-YL)-5-CYANO-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL) METHOXY)(PHENOXY) PHOSPHORYL) AMINO) PROPANOATE

Systematic Name

English

VEKLURY

Brand Name

English

REMDESIVIR [JAN]

Common Name

English

Remdesivir [WHO-DD]

Common Name

English

GS-5734

Code

English

REMDESIVIR [USAN]

Common Name

English

L-ALANINE, N-((S)-HYDROXYPHENOXYPHOSPHINYL)-, 2-ETHYLBUTYL ESTER, 6-ESTER WITH 2-C-(4-AMINOPYRROLO(2,1-F)(1,2,4)TRIAZIN-7-YL)-2,5-ANHYDRO-D-ALTRONONITRILE

Systematic Name

English

REMDESIVIR [ORANGE BOOK]

Common Name

English

2-ETHYLBUTYL (2S)-2-(((S)-(((2R,3S,4R,5R)-5-(4-AMINOPYRROLO(2,1-F)(1,2,4)TRIAZIN-7-YL)-5-CYANO-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHOXY)(PHENOXY)PHOSPHORYL)AMINO)PROPANOATE

Systematic Name

English

2-ETHYLBUTYL N-((S)-(2-C-(4-AMINOPYRROLO(2,1-F)(1,2,4)TRIAZIN-7-YL)-2,5-ANHYDRO-D-ALTRONONITRIL-6-O-YL)PHENOXYPHOSPHORYL)-L-ALANINATE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C281

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

EU-Orphan Drug

EU/3/16/1615

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

FDA ORPHAN DRUG

490515

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

FDA ORPHAN DRUG

739020

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

Code System Code Type Description

CHEBI

145994

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

PRIMARY

DRUG CENTRAL

5376

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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INN

10478

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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FDA UNII

3QKI37EEHE

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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RXCUI

2284718

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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PUBCHEM

121304016

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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NCI_THESAURUS

C152185

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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DAILYMED

3QKI37EEHE

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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USAN

FG-60

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

PRIMARY

EPA CompTox

DTXSID701022537

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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SMS_ID

100000181868

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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DRUG BANK

DB14761

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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CAS

1355050-11-1

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

NON-SPECIFIC STEREOCHEMISTRY

WIKIPEDIA

GS-5734

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

PRIMARY

CAS

1809249-37-3

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

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LACTMED

Remdesivir

Created by admin on Sat Dec 16 19:06:24 GMT 2023 , Edited by admin on Sat Dec 16 19:06:24 GMT 2023

PRIMARY

ACTIVE MOIETY


					3QKI37EEHE

ACTIVE MOIETY (FOR EXCLUSIVITY)


					3W3LMG67VX

Des-phenyl-remdesivir

METABOLITE ACTIVE (PRODRUG)


					1BQK176DT6

GS-441524

METABOLITE ACTIVE (PRODRUG)


					AEL0YED4SU

GS-441524 TRIPHOSPHATE