Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C3H6O3 |
| Molecular Weight | 90.0779 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@@H](O)C(O)=O
InChI
InChIKey=JVTAAEKCZFNVCJ-UWTATZPHSA-N
InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m1/s1
Lactic acid, D- is a natural optical isomer of lactic acid. It is a poorly utilized isomer – 30 to 40% of the dose ingested is excreted in the urine. Lactic acid, D- is known to be harmful to human metabolism and it can result in acidosis and decalcification. D-lactic acidosis, also referred as D-lactate encephalopathy, has been reported in patients with short bowl syndrome. Lactic acid, D- is an interesting precursor for manufacturing heat-resistant polylactic acid (PLA) bioplastics which can be widely used, for example as packaging material, coatings, for textiles or in the automotive industry.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| An enzymatic route to produce pyruvate from lactate. | 2004-11 |
|
| Modelling the electrodialytic recovery of sodium lactate. | 2004-10 |
|
| Effect of intraoperative intravenous crystalloid infusion on postoperative nausea and vomiting after gynaecological laparoscopy: comparison of 30 and 10 ml kg(-1). | 2004-09 |
|
| Factors that contribute to the botulinal safety of reduced-fat and fat-free process chesse products. | 2004-08 |
|
| Evaluation of Staphylococcus aureus growth potential in ham during a slow-cooking process: use of predictions derived from the U.S. Department of Agriculture Pathogen Modeling Program 6.1 predictive model and an inoculation study. | 2004-07 |
|
| Effect of sodium lactate on thermal inactivation of Listeria monocytogenes and Salmonella in ground chicken thigh and leg meat. | 2004-07 |
|
| Effects of ingestion of bicarbonate, citrate, lactate, and chloride on sprint running. | 2004-07 |
|
| Inhibitory effects of organic acid salts on growth of Clostridium perfringens from spore inocula during chilling of marinated ground turkey breast. | 2004-06-01 |
|
| Corticotrophin releasing factor-induced synaptic plasticity in the amygdala translates stress into emotional disorders. | 2004-04-07 |
|
| Selenate reduction in river water by Citerobacter freundii isolated from a selenium-contaminated sediment. | 2004-03-24 |
|
| Development of a novel approach for secondary modelling in predictive microbiology: incorporation of microbiological knowledge in black box polynomial modelling. | 2004-03-15 |
|
| Electrolyte mass balance during CVVH: lactate vs. bicarbonate-buffered replacement fluids. | 2004-03 |
|
| Sodium lactate addition on the quality and shelf life of refrigerated sliced poultry sausage packaged in air or nitrogen atmosphere. | 2004-03 |
|
| Preservation of mitochondrial function during ischemia as a possible mechanism for cardioprotection of diltiazem against ischemia/reperfusion injury. | 2004-02-01 |
|
| Advanced in vitro production of pig blastocysts obtained through determining the time for glucose supplementation. | 2004-02 |
|
| A select group of perpetrators of domestic violence: evidence of decreased metabolism in the right hypothalamus and reduced relationships between cortical/subcortical brain structures in position emission tomography. | 2004-01-15 |
|
| Evaluation of a challenge testing protocol to assess the stability of ready-to-eat cooked meat products against growth of Listeria monocytogenes. | 2004-01-15 |
|
| Antimicrobial activity of enterocin EJ97 against 'Bacillus macroides/Bacillus maroccanus' isolated from zucchini purée. | 2004 |
|
| Lactate depresses sarcolemmal permeability of Ca2+ in intact arterial smooth muscle. | 2003-12-19 |
|
| Flicker light-induced vasodilatation in the human retina: effect of lactate and changes in mean arterial pressure. | 2003-12 |
|
| Radiation (gamma) resistance and postirradiation growth of Listeria monocytogenes suspended in beef bologna containing sodium diacetate and potassium lactate. | 2003-11 |
|
| Determination of serum D-lactic and L-lactic acids in normal subjects and diabetic patients by column-switching HPLC with pre-column fluorescence derivatization. | 2003-11 |
|
| Influence of marinades on survival during storage of acid-adapted and nonadapted Listeria monocytogenes inoculated post-drying on beef jerky. | 2003-09-15 |
|
| Thermal resistances and lactate and diacetate sensitivities of bacteria causing bologna discolouration. | 2003-09-15 |
|
| [Application of sorbilact for treatment of postoperative paralytic ileus in cancer of the esophagus and stomach]. | 2003-09 |
|
| [Experimental provocation of panic attacks as a human experimental model for anxiety]. | 2003-09 |
|
| Effect of intravenous administration of sodium-lactate on retinal blood flow in healthy subjects. | 2003-09 |
|
| [Content of free amino acids in blood plasma of the clean-up personnel at the Chernobyl nuclear power plant accident]. | 2003-08-15 |
|
| Acidosis counteracts the negative inotropic effect of K+ on ventricular muscle strips from the toad Bufo marinus. | 2003-08-04 |
|
| Inhibition of nonproteolytic, psychrotrophic clostridia and anaerobic sporeformers by sodium diacetate and sodium lactate in cook-in-bag turkey breast. | 2003-08 |
|
| Use of organic acids for the control of Clostridium perfringens in cooked vacuum-packaged restructured roast beef during an alternative cooling procedure. | 2003-08 |
|
| Selective enumeration of Lactobacillus delbrueckii ssp. bulgaricus, Streptococcus thermophilus, Lactobacillus acidophilus, bifidobacteria, Lactobacillus casei, Lactobacillus rhamnosus, and propionibacteria. | 2003-07 |
|
| Correlates of therapeutic response in panic disorder presenting with palpitations: heart rate variability, sleep, and placebo effect. | 2003-07 |
|
| pH and energy dependent transport of ketoprofen across rat jejunum in vitro. | 2003-07 |
|
| Lactate: a preferred fuel for human brain metabolism in vivo. | 2003-06 |
|
| Acid diffusion through extracellular polysaccharides produced by various mutants of Streptococcus mutans. | 2003-06 |
|
| Coping strategies of panic and control subjects undergoing lactate infusion during magnetic resonance imaging confinement. | 2003-05-24 |
|
| [Na+ overload-induced mitochondrial dysfunction in myocardial ischemia/reperfusion injury]. | 2003-05 |
|
| Growth and germination of proteolytic Clostridium botulinum in vegetable-based media. | 2003-05 |
|
| Predictive model for the combined effect of temperature, sodium lactate, and sodium diacetate on the heat resistance of Listeria monocytogenes in beef. | 2003-05 |
|
| Intravenous fluid loading with or without supplementary dextrose does not prevent nausea, vomiting and pain after laparoscopy. | 2003-05 |
|
| Erosion of water-based cements evaluated by volumetric and gravimetric methods. | 2003-05 |
|
| High production system of the antibacterial peptide PLG-1. | 2003-04-05 |
|
| Thermal inactivation of Escherichia coli O157:H7 in ground beef supplemented with sodium lactate. | 2003-04 |
|
| Peritoneal dialysis solutions inhibit the differentiation and maturation of human monocyte-derived dendritic cells: effect of lactate and glucose-degradation products. | 2003-04 |
|
| Glucose-mediated induction of TGF-beta 1 and MCP-1 in mesothelial cells in vitro is osmolality and polyol pathway dependent. | 2003-04 |
|
| Effects of acid adaptation and modified marinades on survival of postdrying Salmonella contamination on beef jerky during storage. | 2003-03 |
|
| Inhibition of arginine synthesis by urea: a mechanism for arginine deficiency in renal failure which leads to increased hydroxyl radical generation. | 2003-02 |
|
| Total calcium content of sacs associated with inguinal hernia, hydrocele or undescended testis reflects differences dictated by programmed cell death. | 2003 |
|
| Fluorimetric assay of D-lactate. | 1992-10 |
Patents
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
FDA ORPHAN DRUG |
872422
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DTXSID0047030
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | |||
|
SUB179792
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | |||
|
61503
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | |||
|
m6653
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | Merck Index | ||
|
DB03066
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | |||
|
1742994
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | |||
|
100000165898
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | |||
|
3Q6M5SET7W
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | |||
|
10326-41-7
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | |||
|
42111
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | |||
|
3Q6M5SET7W
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY | |||
|
233-713-2
Created by
admin on Mon Mar 31 20:58:45 GMT 2025 , Edited by admin on Mon Mar 31 20:58:45 GMT 2025
|
PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
