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Details

Stereochemistry ABSOLUTE
Molecular Formula C16H28N4O6
Molecular Weight 372.4167
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of KP-1461

SMILES

CCCCCCCOC(=O)NC1=NC(=O)N(CN1)[C@H]2C[C@H](O)[C@@H](CO)O2

InChI

InChIKey=SZWIAFVYPPMZML-YNEHKIRRSA-N
InChI=1S/C16H28N4O6/c1-2-3-4-5-6-7-25-16(24)19-14-17-10-20(15(23)18-14)13-8-11(22)12(9-21)26-13/h11-13,21-22H,2-10H2,1H3,(H2,17,18,19,23,24)/t11-,12+,13+/m0/s1

HIDE SMILES / InChI

Description

KP-1461 is a prodrug of KP-1212, an antiviral agent developed for the treatment of human immunodeficiency virus (HIV) infection. KP-1212 induces an increase in the HIV mutation rate thus leading to viral ablation.

Originator

Approval Year

PubMed