ESPROQUIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C14H21NOS
Molecular Weight	251.388
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ESPROQUIN

Structure Search

SMILES

CC[S+]([O-])CCCN1CCC2=CC=CC=C2C1

InChI

InChIKey=YKKQKMDOWYCXEX-UHFFFAOYSA-N

InChI=1S/C14H21NOS/c1-2-17(16)11-5-9-15-10-8-13-6-3-4-7-14(13)12-15/h3-4,6-7H,2,5,8-12H2,1H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4146907 | https://www.ncbi.nlm.nih.gov/pubmed/4698571

Esproquine is a tetrahydroisoquinoline derivative. It exerts positive inotropic effect and increases arterial pressure.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Preparation and cardiovascular actions of a group of tetrahydroisoquinoline derivatives.	1973-07	4146907
Positive inotropic effect of oral esproquin in normal subjects.	1973-05-01	4698571

Sample Use Guides

In Vivo Use Guide

single oral doses of 100, 200, or 300 mg esproquine

Route of Administration: Oral

Name

Type

Language

ESPROQUIN

Common Name

English

ESPROQUINE

Preferred Name

English

2-(3-ETHYLSULFINYLPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE

Systematic Name

English

esproquine [INN]

Common Name

English

ISOQUINOLINE, 2-((3-(ETHYLSULFINYL)PROPYL)-1,2,3,4-TETRAHYDRO-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29713

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

Code System Code Type Description

CAS

37517-33-2

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

PRIMARY

SMS_ID

100000082380

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

PRIMARY

INN

3517

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

PRIMARY

FDA UNII

3JYK9XFM9K

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

PRIMARY

ChEMBL

CHEMBL2110833

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

PRIMARY

EVMPD

SUB07240MIG

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

PRIMARY

EPA CompTox

DTXSID40865872

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

PRIMARY

NCI_THESAURUS

C72568

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

PRIMARY

PUBCHEM

31951

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

PRIMARY

MESH

C002967

Created by admin on Mon Mar 31 18:19:07 GMT 2025 , Edited by admin on Mon Mar 31 18:19:07 GMT 2025

PRIMARY

ACTIVE MOIETY


					3JYK9XFM9K

ESPROQUIN

SALT/SOLVATE (PARENT)


					1P9E5C9137

ESPROQUIN HYDROCHLORIDE