U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C29H26FN7O
Molecular Weight 507.5614
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LENRISPODUN

SMILES

[H][C@@]12CCC[C@]1([H])N3C(=N2)N(C)C(=O)C4=C(NC5=CC=CC=C5)N(CC6=CC=C(C=C6)C7=NC(F)=CC=C7)N=C34

InChI

InChIKey=BBIPVJCGIASXJB-PKTZIBPZSA-N
InChI=1S/C29H26FN7O/c1-35-28(38)25-26(31-20-7-3-2-4-8-20)36(34-27(25)37-23-11-5-10-22(23)33-29(35)37)17-18-13-15-19(16-14-18)21-9-6-12-24(30)32-21/h2-4,6-9,12-16,22-23,31H,5,10-11,17H2,1H3/t22-,23+/m1/s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
3.4E-5 µM [Ki]
3.8E-4 µM [Ki]
3.7E-5 µM [Ki]
3.1 µM [Ki]
0.033 µM [Ki]
Name Type Language
LENRISPODUN
USAN   INN  
Official Name English
IC-200214
Code English
ITI-214 FREE BASE
Code English
IC200214
Code English
CYCLOPENT(4,5)IMIDAZO(1,2-A)PYRAZOLO(4,3-E)PYRIMIDIN-4(2H)-ONE, 2-((4-(6-FLUORO-2-PYRIDINYL)PHENYL)METHYL)-5,6A,7,8,9,9A-HEXAHYDRO-5-METHYL-3-(PHENYLAMINO)-, (6AR,9AS)-
Systematic Name English
LENRISPODUN [USAN]
Common Name English
ITI-214
Code English
lenrispodun [INN]
Common Name English
(6AR,9AS)-2-((4-(6-FLUORO-2-PYRIDINYL)PHENYL)METHYL)-5,6A,7,8,9,9AHEXAHYDRO- 5-METHYL-3-(PHENYLAMINO)CYCLOPENT(4,5)IMIDAZO(1,2-A)PYRAZOLO(4,3- E)PYRIMIDIN-4(2H)-ONE
Systematic Name English
ITI-214F
Code English
Code System Code Type Description
PUBCHEM
42639643
Created by admin on Sat Dec 16 10:54:57 GMT 2023 , Edited by admin on Sat Dec 16 10:54:57 GMT 2023
PRIMARY
NCI_THESAURUS
C177065
Created by admin on Sat Dec 16 10:54:57 GMT 2023 , Edited by admin on Sat Dec 16 10:54:57 GMT 2023
PRIMARY
USAN
GH-75
Created by admin on Sat Dec 16 10:54:57 GMT 2023 , Edited by admin on Sat Dec 16 10:54:57 GMT 2023
PRIMARY
INN
11635
Created by admin on Sat Dec 16 10:54:57 GMT 2023 , Edited by admin on Sat Dec 16 10:54:57 GMT 2023
PRIMARY
FDA UNII
3GBO34D1BE
Created by admin on Sat Dec 16 10:54:57 GMT 2023 , Edited by admin on Sat Dec 16 10:54:57 GMT 2023
PRIMARY
CAS
1160521-50-5
Created by admin on Sat Dec 16 10:54:57 GMT 2023 , Edited by admin on Sat Dec 16 10:54:57 GMT 2023
PRIMARY
SMS_ID
300000028890
Created by admin on Sat Dec 16 10:54:57 GMT 2023 , Edited by admin on Sat Dec 16 10:54:57 GMT 2023
PRIMARY
DRUG BANK
DB15039
Created by admin on Sat Dec 16 10:54:57 GMT 2023 , Edited by admin on Sat Dec 16 10:54:57 GMT 2023
PRIMARY