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Details

Stereochemistry RACEMIC
Molecular Formula C19H20INO2
Molecular Weight 421.2721
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IBE-2254

SMILES

OC1=C(I)C=C(CCNCC2CCC3=C(C=CC=C3)C2=O)C=C1

InChI

InChIKey=DUOOAUBZMQZYLO-UHFFFAOYSA-N
InChI=1S/C19H20INO2/c20-17-11-13(5-8-18(17)22)9-10-21-12-15-7-6-14-3-1-2-4-16(14)19(15)23/h1-5,8,11,15,21-22H,6-7,9-10,12H2

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Effects of quinidine and verapamil on human cardiovascular alpha1-adrenoceptors.
1998 Apr 7
Vascular alpha1-adrenoceptor subtype selectivity and alpha1-blocker-induced orthostatic hypotension.
1998 May
Differential antagonism by conotoxin rho-TIA of contractions mediated by distinct alpha1-adrenoceptor subtypes in rat vas deferens, spleen and aorta.
2005 Jan 31
Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies.
2006 Jan 11
1-Arylpiperazinyl-4-cyclohexylamine derived isoindole-1,3-diones as potent and selective alpha-1a/1d adrenergic receptor ligands.
2007 Mar 15
Patents
Name Type Language
IBE-2254
Common Name English
2-(P-(4-HYDROXY-3-(125I)IODOPHENYL)ETHYLAMINOMETHYL)-TETRALONE
Common Name English
M-IODO-HEAT
Common Name English
2-((2-(4-HYDROXY-3-IODANYLPHENYL)ETHYLAMINO)METHYL)-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE
Systematic Name English
1(2H)-NAPHTHALENONE, 3,4-DIHYDRO-2-(((2-(4-HYDROXY-3-IODOPHENYL)ETHYL)AMINO)METHYL)-
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID40915164
Created by admin on Fri Dec 15 16:49:47 GMT 2023 , Edited by admin on Fri Dec 15 16:49:47 GMT 2023
PRIMARY
CAS
95034-25-6
Created by admin on Fri Dec 15 16:49:47 GMT 2023 , Edited by admin on Fri Dec 15 16:49:47 GMT 2023
PRIMARY
PUBCHEM
10093628
Created by admin on Fri Dec 15 16:49:47 GMT 2023 , Edited by admin on Fri Dec 15 16:49:47 GMT 2023
PRIMARY
FDA UNII
3EGK3ZND2L
Created by admin on Fri Dec 15 16:49:47 GMT 2023 , Edited by admin on Fri Dec 15 16:49:47 GMT 2023
PRIMARY