Stereochemistry | ABSOLUTE |
Molecular Formula | C37H70N2O12 |
Molecular Weight | 734.9579 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 18 / 18 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]2[C@H](C)[C@@H](O[C@]3([H])O[C@H](C)C[C@H](NC)[C@H]3O)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]2C
InChI
InChIKey=FZYUKBLYECHAGN-HOQMJRDDSA-N
InChI=1S/C37H70N2O12/c1-14-26-37(10,45)30(41)23(6)39(12)18-19(2)16-35(8,44)32(51-34-28(40)25(38-11)15-20(3)47-34)21(4)29(22(5)33(43)49-26)50-27-17-36(9,46-13)31(42)24(7)48-27/h19-32,34,38,40-42,44-45H,14-18H2,1-13H3/t19-,20-,21+,22-,23-,24+,25+,26-,27+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
N’-(desmethyl)azithromycin (CP-64434 hydrate) is the metabolite of azithromycin. Azithromycin is an effective therapeutic agent for oral treatment of sexually transmitted diseases, upper and lower respiratory tract infections, and skin and skin structure infections. 0.1 and 7.6% of azithromycin dose are excreted as N’-(desmethyl)azithromycin during a day in urine and feces, respectively. 2.9% of dose - biliary excretion.
Approval Year
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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