METAMELFALAN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C13H18Cl2N2O2
Molecular Weight	305.2
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N[C@@H](CC1=CC(=CC=C1)N(CCCl)CCCl)C(O)=O

InChI

InChIKey=QDGAVODICPCDMU-LBPRGKRZSA-N

InChI=1S/C13H18Cl2N2O2/c14-4-6-17(7-5-15)11-3-1-2-10(8-11)9-12(16)13(18)19/h1-3,8,12H,4-7,9,16H2,(H,18,19)/t12-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://pubs.rsc.org/en/content/articlelanding/1954/jr/jr9540002409#!divAbstract | https://www.ncbi.nlm.nih.gov/pubmed/14174040 | https://medkoo.com/products/20742 | https://link.springer.com/book/10.1007/978-1-4757-2085-3#about

Metamelfalan is an antineoplastic agent. Metamelfalan is the meta form of the levo isomer melphalan. Metamelfalan causes crosslinking of DNA, thereby preventing DNA replication and eventually cellular proliferation.

Approval Year

PubMed

Title	Date	PubMed

Name

Type

Language

METAMELFALAN

Official Name

English

ALANINE, 3-(M-(BIS(2-CHLOROETHYL)AMINO)PHENYL)-, L-

Systematic Name

English

L-M-SARCOLYSIN

Common Name

English

3-(M-(BIS(2-CHLOROETHYL)AMINO)PHENYL)-L-ALANINE

Systematic Name

English

Metamelfalan [WHO-DD]

Common Name

English

L-PHENYLALANINE, 3-(BIS(2-CHLOROETHYL)AMINO)-

Systematic Name

English

NSC-67781

Code

English

3-(BIS(2-CHLOROETHYL)AMINO)-L-PHENYLALANINE

Systematic Name

English

metamelfalan [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C697