Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H11N |
| Molecular Weight | 181.2331 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=CC=C2C(CC3=CC=CC=C23)=C1
InChI
InChIKey=CFRFHWQYWJMEJN-UHFFFAOYSA-N
InChI=1S/C13H11N/c14-11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8H,7,14H2
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Study on the mutagenicity and antimutagenicity of beta-ionone in the Salmonella/microsome assay. | 2006-04 |
|
| Metabolic activation of bladder procarcinogens, 2-aminofluorene, 4-aminobiphenyl, and benzidine by Pseudomonas aeruginosa and other human endogenous bacteria. | 2006-04 |
|
| Berberine inhibits arylamine N-acetyltransferase activity and gene expression in Salmonella typhi. | 2005-10 |
|
| Involvement of molybdenum hydroxylases in reductive metabolism of nitro polycyclic aromatic hydrocarbons in mammalian skin. | 2005-09 |
|
| Evaluation of mutagenic and antimutagenic activities of alpha-bisabolol in the Salmonella/microsome assay. | 2005-08-01 |
|
| Oral administration of paclitaxel affects the distribution and metabolism of 2-aminofluorene in various tissues of Sprague-Dawley rats. | 2005-08 |
|
| Diallyl disulfide inhibits N-acetyltransferase activity and gene expression in human esophagus epidermoid carcinoma CE 81T/VGH cells. | 2005-07 |
|
| Time-resolved resonance Raman observation of the 2-fluorenylnitrenium ion reaction with guanosine to form a C8 intermediate. | 2005-06-15 |
|
| Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes. | 2005-06-01 |
|
| Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines. | 2005-05 |
|
| Wogonin inhibits N-acetyltransferase activity and gene expression in human leukemia HL-60 cells. | 2005-04-09 |
|
| Effects of aspirin on the in vitro and in vivo acetylation of 2-aminofluorene in Sprague-Dawley rats. | 2005-03-31 |
|
| N-acetyltransferase is involved in baicalein-induced N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in human leukemia HL-60 cells. | 2005-03-31 |
|
| Ellagic acid inhibits growth and arylamine N-acetyltransferase activity and gene expression in Staphylococcus aureus. | 2005-03-31 |
|
| Effects of ellagic acid by oral administration on distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats. | 2005-03-31 |
|
| Incorporation of N2-deoxyguanosine metabolic adducts of 2-aminonaphthalene and 2-aminofluorene into oligomeric DNA. | 2005-03 |
|
| Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1. | 2005-02 |
|
| Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening. | 2005-01-15 |
|
| Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase. | 2005-01-15 |
|
| Effects of exposure to diesel exhaust particles (DEP) on pulmonary metabolic activation of mutagenic agents. | 2004-12-12 |
|
| Antimutagenicity of coriander (Coriandrum sativum) juice on the mutagenesis produced by plant metabolites of aromatic amines. | 2004-11-02 |
|
| Evidence for arylamine N-acetyltransferase activity in Klebsiella pneumoniae. | 2004-08 |
|
| N-ethylphenyl acetamide (EPA) inhibits DNA synthesis and N-acetylation of 2-aminofluorene in human colon tumor cells (colo 205). | 2004-07-28 |
|
| Shikonin inhibits the growth and N-acetylation of 2-aminofluorene in Helicobacter pylori from ulcer patients. | 2004-07-28 |
|
| N-acetyltransferase activity is involved in paclitaxel-induced N-acetylation of 2-aminofluorene in human bladder cancer cells (T24). | 2004-07-28 |
|
| Formation and reduction of aryl and heterocyclic nitroso compounds and significance in the flux of hydroxylamines. | 2004-04 |
|
| PCR and flow cytometric analysis of paclitaxel-inhibited arylamine N-acetyltransferase activity and gene expression in human osteogenic sarcoma cells (U-2 OS). | 2004-03-16 |
|
| The inhibition of N-acetyltransferase activity and gene expression in human bladder cancer cells (T24) by shikonin. | 2004-03-12 |
|
| Mass spectrometric investigation of the mechanism of inactivation of hamster arylamine N-acetyltransferase 1 by N-hydroxy-2-acetylaminofluorene. | 2004-03 |
|
| Inhibition of N-acetyltransferase activity and gene expression in human colon cancer cell lines by diallyl sulfide. | 2004-02 |
|
| Human acetyl CoA:arylamine N-acetyltransferase variants generated by random mutagenesis. | 2004-01 |
|
| Effects of (-)-menthol on the distribution and metabolism of 2-aminofluorene in various tissues of Sprague-Dawley rats. | 2003-11-06 |
|
| Effects of DNA adduct structure and sequence context on strand opening of repair intermediates and incision by UvrABC nuclease. | 2003-11-04 |
|
| Arylamine N-acetyltransferases: covalent modification and inactivation of hamster NAT1 by bromoacetamido derivatives of aniline and 2-aminofluorene. | 2003-11 |
|
| Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells. | 2003-09 |
|
| Curcumin decreases the DNA adduct formation, arylamines N-acetyltransferase activity and gene expression in human colon tumor cells (colo 205). | 2003-08-22 |
|
| N-acetyltransferase is involved in gypenosides-induced N-acetylation of 2-aminofluorene and DNA adduct formation in human cervix epidermoid carcinoma cells (Ca Ski). | 2003-08-22 |
|
| Paclitaxel affects the amounts of the N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in Sprague-Dawley rats. | 2003-06-10 |
|
| Paclitaxel (taxol) inhibits the arylamine N-acetyltransferase activity and gene expression (mRNA NAT1) and 2-aminofluorene-DNA adduct formation in human bladder carcinoma cells (T24 and TSGH 8301). | 2003-06 |
|
| Curcumin inhibited the arylamines N-acetyltransferase activity, gene expression and DNA adduct formation in human lung cancer cells (A549). | 2003-06 |
|
| Neonatal ontogeny of murine arylamine N-acetyltransferases: implications for arylamine genotoxicity. | 2003-06 |
|
| Characterization of pulmonary CYP4B2, specific catalyst of methyl oxidation of 3-methylindole. | 2003-05 |
|
| Luteolin induces N-acetylation and DNA adduct of 2-aminofluorene accompanying N-acetyltransferase activity and gene expression in human bladder cancer T24 cell line. | 2003-04-12 |
|
| Xanthine oxidase-catalyzed metabolism of 2-nitrofluorene, a carcinogenic air pollutant, in rat skin. | 2003-04 |
|
| Time-resolved resonance Raman and density functional study of an azirine intermediate in the 2-fluorenylnitrene ring-expansion reaction to form a dehydroazepine product. | 2003-03-17 |
|
| Mutagenic and antimutagenic potential of the medicinal plants M. laevigata and C. xanthocarpa. | 2003-03 |
|
| Bioassay-guided isolation of antimutagenic factors from fruits of Terminalia bellerica. | 2003 |
|
| Studies on correlation of antimutagenic and antiproliferative activities of Juglans regia L. | 2003 |
|
| Activities of cytochrome p450 enzymes in liver and kidney microsomes from systemic carnitine deficiency mice with a gene mutation of carnitine/organic cation transporter. | 2002 |
|
| Reversion mutation in dark variants of luminous bacteria and its application in gene toxicant monitoring. | 2002 |
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| Code System | Code | Type | Description | ||
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205-817-8
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DTXSID1049223
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4026
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2-Aminofluorene
Created by
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1539
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C012177
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153-78-6
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3A69OS195N
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12274
Created by
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SUBSTANCE RECORD
