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Details

Stereochemistry ACHIRAL
Molecular Formula C6H3I2NO3
Molecular Weight 390.9021
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DISOPHENOL

SMILES

c1c(cc(c(c1I)O)I)N(=O)=O

InChI

InChIKey=UVGTXNPVQOQFQW-UHFFFAOYSA-N
InChI=1S/C6H3I2NO3/c7-4-1-3(9(11)12)2-5(8)6(4)10/h1-2,10H

HIDE SMILES / InChI
Disophenol is a drug used in veterinary medicine recommended for use in the treatment of dogs infested with hook worms (Ancylostoma caninum, A. braziliense and Uncinuriu stenocephala) and cats infested with the hookworm A. tubaeforme.

Approval Year

Targets

Targets

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
ANCYLOL

Approved Use

The drug is used for the treatment of both dogs infested with hookworms (including Ancylostoma caninum, A. braziliense and Uncinaria stenocephala) and cats infested with the hookworm A. tubaeforme.

Launch Date

-1.75910404E11
PubMed

PubMed

TitleDatePubMed
2,6-Diiodo-4-nitrophenol, 2,6-diiodo-4-nitrophenyl acetate and 2,6-diiodo-4-nitroanisole: interplay of hydrogen bonds, iodo-nitro interactions and aromatic pi-pi-stacking interactions to give supramolecular structures in one, two and three dimensions.
2002 Aug
Patents

Patents

Sample Use Guides

Dogs and cats: Disophenol is administered subcutaneously at a dosage level equivalent to 4.5 milligrams of disophenol per pound of body weight. A second treatment may be indicated 21 days after the initial treatment.
Route of Administration: Other
In Vitro Use Guide
Disophenol produced contracture of the rat cardiac muscle at concentrations of 100 and 1000 ng/ml and at the latter dose diastolic tension after 60 min perfusion was approximately 300 per cent of its initial value.
Name Type Language
DISOPHENOL
MART.   MI  
Common Name English
DISOPHEN
Brand Name English
ANCYLOL
Brand Name English
SYNGAMIX
Brand Name English
IODOFEN
Brand Name English
PHENOL, 2,6-DIIODO-4-NITRO-
Systematic Name English
DISOFEN
Brand Name English
DISOPHENOL [MART.]
Common Name English
NSC-94733
Code English
DISOPHENOL [MI]
Common Name English
2,6-DIIODO-4-NITROPHENOL
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C250
Created by admin on Fri Jun 25 22:11:12 UTC 2021 , Edited by admin on Fri Jun 25 22:11:12 UTC 2021
Code System Code Type Description
CAS
305-85-1
Created by admin on Fri Jun 25 22:11:12 UTC 2021 , Edited by admin on Fri Jun 25 22:11:12 UTC 2021
PRIMARY
MERCK INDEX
M4671
Created by admin on Fri Jun 25 22:11:12 UTC 2021 , Edited by admin on Fri Jun 25 22:11:12 UTC 2021
PRIMARY Merck Index
ECHA (EC/EINECS)
206-170-4
Created by admin on Fri Jun 25 22:11:12 UTC 2021 , Edited by admin on Fri Jun 25 22:11:12 UTC 2021
PRIMARY
PUBCHEM
9370
Created by admin on Fri Jun 25 22:11:12 UTC 2021 , Edited by admin on Fri Jun 25 22:11:12 UTC 2021
PRIMARY
EPA CompTox
305-85-1
Created by admin on Fri Jun 25 22:11:12 UTC 2021 , Edited by admin on Fri Jun 25 22:11:12 UTC 2021
PRIMARY
NCI_THESAURUS
C75215
Created by admin on Fri Jun 25 22:11:12 UTC 2021 , Edited by admin on Fri Jun 25 22:11:12 UTC 2021
PRIMARY
FDA UNII
39S5ZJ6SYN
Created by admin on Fri Jun 25 22:11:12 UTC 2021 , Edited by admin on Fri Jun 25 22:11:12 UTC 2021
PRIMARY