Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C18H24O12 |
Molecular Weight | 432.376 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 9 / 9 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12[C@@H](O)C=C(COC(C)=O)[C@@]1([H])[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(O)=O
InChI
InChIKey=DGDWCRWJRNMRKX-DILZHRMZSA-N
InChI=1S/C18H24O12/c1-6(20)27-4-7-2-9(21)12-8(16(25)26)5-28-17(11(7)12)30-18-15(24)14(23)13(22)10(3-19)29-18/h2,5,9-15,17-19,21-24H,3-4H2,1H3,(H,25,26)/t9-,10+,11+,12-,13+,14-,15+,17-,18-/m0/s1
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: map04064 |
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Target ID: map04350 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30668407 |
PubMed
Title | Date | PubMed |
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Increased plasma 3,5,3'-triiodothyronine sulfate in rats with inhibited type I iodothyronine deiodinase activity, as measured by radioimmunoassay. | 1989 Feb |
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An LC-MS method for simultaneous determination of five iridoids from Zhi-zi-chi Decoction in rat brain microdialysates and tissue homogenates: towards an in depth study for its antidepressive activity. | 2014 Aug 15 |
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[Study on chemical constituents of iridoids from eucommiae folium]. | 2014 Feb |
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Isolation and purification of six iridoid glycosides from gardenia jasminoides fruit by medium-pressure liquid chromatography combined with macroporous resin chromatography. | 2015 Dec |
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Analysis of Organic Acids, Deacetyl Asperulosidic Acid and Polyphenolic Compounds as a Potential Tool for Characterization of Noni (Morinda citrifolia) Products. | 2015 Nov |
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Acousto-optic tunable filter near-infrared spectroscopy for in-line monitoring liquid-liquid extraction of Gardenia jasminoides Ellis based on statistical analysis. | 2015 Oct |
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[Identification of Oldenlandia diffusa by UPLC Fingerprint Coupled with Chemometrics Methods]. | 2016 Apr |
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Morinda citrifolia Linn. Reduces Parasite Load and Modulates Cytokines and Extracellular Matrix Proteins in C57BL/6 Mice Infected with Leishmania (Leishmania) amazonensis. | 2016 Aug |
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α-Glucosidase and α-Amylase Inhibitors from Arcytophyllum thymifolium. | 2016 Aug 26 |
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LC/MS/MS determination and pharmacokinetic study of iridoid glycosides monotropein and deacetylasperulosidic acid isomers in rat plasma after oral administration of Morinda officinalis extract. | 2016 Feb |
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Phytochemistry, micromorphology and bioactivities of Ajuga chamaepitys (L.) Schreb. (Lamiaceae, Ajugoideae): Two new harpagide derivatives and an unusual iridoid glycosides pattern. | 2016 Sep |
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Anti-malarial synergy of secondary metabolites from Morinda lucida Benth. | 2017 Mar 6 |
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Mid-infrared and near-infrared spectroscopy for rapid detection of Gardeniae Fructus by a liquid-liquid extraction process. | 2017 Oct 25 |
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Iridoids and sfingolipids from Hedyotis diffusa. | 2018 Jan |
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Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages. | 2018 Jul 12 |
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Simultaneous Analysis of Iridoid Glycosides and Anthraquinones in Morinda officinalis Using UPLC-QqQ-MS/MS and UPLC-Q/TOF-MS(E). | 2018 May 3 |
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Pharmacokinetics and tissue distribution of monotropein and deacetyl asperulosidic acid after oral administration of extracts from Morinda officinalis root in rats. | 2018 Oct 24 |
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In silico screening of anthraquinones from Prismatomeris memecyloides as novel phosphodiesterase type-5 inhibitors (PDE-5Is). | 2018 Oct-Dec |
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Anti-renal fibrosis effect of asperulosidic acid via TGF-β1/smad2/smad3 and NF-κB signaling pathways in a rat model of unilateral ureteral obstruction. | 2019 Feb |
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Anti-inflammatory constituents from Psychotria prainii H. Lév. | 2019 Mar |
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25368-11-0
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SUBSTANCE RECORD