PHOSPHATIDYL SERINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C42H82NO10P
Molecular Weight	792.0749
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC

InChI

InChIKey=TZCPCKNHXULUIY-RGULYWFUSA-N

InChI=1S/C42H82NO10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49)/t38-,39+/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3568613 | https://www.ncbi.nlm.nih.gov/pubmed/17665876

DB00144 (1-propionyl-2-butyl phosphatidylserine) is a phosphatidylserine derivative. It consists of a propionic and butyric acid residues attached in ester linkage to the first and second carbon of glycerol and serine attached through a phosphodiester linkage to the third carbon of the glycerol. DB00144 is not found in natural sources of phosphatidylserine, which contain fatty acids with a length of 20-22 carbon atoms. DB00144 was detected as one of the cellular metabolites in murine myocardium.

Approval Year

PubMed

Title	Date	PubMed
Thyroxine signal transduction in liver cells involves phospholipase C and phospholipase D activation. Genomic independent action of thyroid hormone.	2001	11312999
Flow cytometry in analysis of cell cycle and apoptosis.	2001 Apr	11309699
Molecular consequences of activated microglia in the brain: overactivation induces apoptosis.	2001 Apr	11279274
Dipole potentials indicate restructuring of the membrane interface induced by gadolinium and beryllium ions.	2001 Apr	11259298
Pulmonary surfactant protein SP-B is significantly more immunoreactive in anionic than in zwitterionic bilayers.	2001 Apr 13	11311247
Apoptotic cell debris and phosphatidylserine-containing lipid vesicles induce apolipoprotein J (clusterin) gene expression in vital fibroblasts.	2001 Apr 15	11281639
How do lipases and esterases work: the electrostatic contribution.	2001 Feb 13	11165360
Cholesterol favors phase separation of sphingomyelin.	2001 Feb 15	11254209
Selective protein interactions with phosphatidylserine containing liposomes alter the steric stabilization properties of poly(ethylene glycol).	2001 Feb 9	11342147
Modulation of apoptosis by procaspase-2 short isoform: selective inhibition of chromatin condensation, apoptotic body formation and phosphatidylserine externalization.	2001 Jan 11	11313953
Identification of novel membrane-bound phospholipase D from Streptoverticillium cinnamoneum, possessing only hydrolytic activity.	2001 Jan 15	11341956
Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells.	2001 Jul 6	11335714
Role of hydrophobic residues in the C1b domain of protein kinase C delta on ligand and phospholipid interactions.	2001 Jun 1	11278612
Physical properties of erythrocyte ghosts that determine susceptibility to secretory phospholipase A2.	2001 Jun 22	11294853
Enhancement of transport-dependent decarboxylation of phosphatidylserine by S100B protein in permeabilized Chinese hamster ovary cells.	2001 Jun 29	11320095
Nuclear diacylglycerol kinase-theta is activated in response to alpha-thrombin.	2001 Jun 29	11309392
Brain and hippocampus fatty acid composition in phospholipid classes of aged-relative cognitive deficit rats.	2001 Mar	11334555
C2 domains from different Ca2+ signaling pathways display functional and mechanistic diversity.	2001 Mar 13	11258923
Phospholipids released from activated platelets improve platelet aggregation and endothelial cell migration.	2001 May	11304418

Patents

Name

Type

Language

PHOSPHATIDYL SERINE

Common Name

English

Phosphatidyl serine [WHO-DD]

Common Name

English

PHOSPHATIDYLSERINE [INCI]

Common Name

English

PHOSPHATIDYLSERINE

Official Name

English

PHOSPHOTIDYLSERINE [VANDF]

Common Name

English

PHOSPHATIDYLSERINE [VANDF]

Common Name

English

PHOSPHOTIDYLSERINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C68340