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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H23FN4O8
Molecular Weight 441.3989
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PIFLUFOLASTAT F-18

SMILES

C(CCN=C(c1ccc(F)nc1)O)C[C@@]([H])(C(=O)O)N=C(N[C@@]([H])(CCC(=O)O)C(=O)O)O

InChI

InChIKey=OLWVRJUNLXQDSP-MVBOSPHXSA-N
InChI=1S/C18H23FN4O8/c19-13-6-4-10(9-21-13)15(26)20-8-2-1-3-11(16(27)28)22-18(31)23-12(17(29)30)5-7-14(24)25/h4,6,9,11-12H,1-3,5,7-8H2,(H,20,26)(H,24,25)(H,27,28)(H,29,30)(H2,22,23,31)/t11-,12-/m0/s1/i19-1

HIDE SMILES / InChI
DCFPYL F-18 is an urea-based radiotracer composed of the prostate-specific membrane antigen (PSMA)-targeting agent DCFPyL and labeled with the positron-emitting isotope, fluorine F 18, that can potentially be used for positron-emitting tomography (PET) imaging. Upon administration of fluorine F 18 DCFPyL, the DCFPyL moiety binds to PSMA expressed on tumor cells. The fluorine F 18 moiety facilitates PET imaging of PSMA-expressing tumor cells. DCFPYL F-18 is investigated in a number of clinical trials in patients with prostate cancer and neuroendocrine tumors.

Approval Year

Name Type Language
PIFLUFOLASTAT F-18
Common Name English
PYLARIFY
Brand Name English
18F-DCFPYL
Common Name English
PIFLUFOLASTAT F18
Common Name English
(18F)DCFPYL
Common Name English
L-GLUTAMIC ACID, N-((((1S)-1-CARBOXY-5-(((6-(FLUORO-18F)-3-PYRIDINYL)CARBONYL)AMINO)PENTYL)AMINO)CARBONYL)-
Systematic Name English
DCFPYL F-18
Common Name English
2-(3-(1-CARBOXY-5-((6-(18F)FLUORO-PYRIDINE-3-CARBONYL)-AMINO)-PENTYL)-UREIDO)-PENTANEDIOIC ACID
Systematic Name English
Code System Code Type Description
FDA UNII
3934EF02T7
Created by admin on Fri Jun 25 21:29:12 UTC 2021 , Edited by admin on Fri Jun 25 21:29:12 UTC 2021
PRIMARY
DRUG BANK
DB14805
Created by admin on Fri Jun 25 21:29:12 UTC 2021 , Edited by admin on Fri Jun 25 21:29:12 UTC 2021
PRIMARY
EVMPD
SUB189818
Created by admin on Fri Jun 25 21:29:12 UTC 2021 , Edited by admin on Fri Jun 25 21:29:12 UTC 2021
PRIMARY
CAS
1207181-29-0
Created by admin on Fri Jun 25 21:29:12 UTC 2021 , Edited by admin on Fri Jun 25 21:29:12 UTC 2021
PRIMARY
PUBCHEM
52950901
Created by admin on Fri Jun 25 21:29:12 UTC 2021 , Edited by admin on Fri Jun 25 21:29:12 UTC 2021
PRIMARY