Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C16H26O2 |
| Molecular Weight | 250.3764 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12CC(=O)O[C@]1(C)CC[C@@]3([H])C(C)(C)CCC[C@]23C
InChI
InChIKey=IMKJGXCIJJXALX-SHUKQUCYSA-N
InChI=1S/C16H26O2/c1-14(2)7-5-8-15(3)11(14)6-9-16(4)12(15)10-13(17)18-16/h11-12H,5-10H2,1-4H3/t11-,12+,15-,16+/m0/s1
DescriptionCurator's Comment: description was created based on several sources, including
US Patent Application No. 2010/0183527 A1
Curator's Comment: description was created based on several sources, including
US Patent Application No. 2010/0183527 A1
Sclareolide is a sesquiterpene lactone natural product derived from various plant sources including Salvia sclarea, Salvia yosgadensis, and cigar tobacco. Sclareolide demonstrated good antibacterial activity against common human pathogens, including Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Enterococcus faecalis. Sclareolide is not generally known for its bioactive properties. Instead, it is mostly used as a fixative or base in the perfume industry. It is also used in cosmetics, because it is thought to contribute to tanning of skin and/or darkening of hair.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Enantiospecific synthesis of the antituberculosis marine sponge metabolite (+)-puupehenone. The arenol oxidative activation route. | 2002 Oct 31 |
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| A study on the synthesis of antiangiogenic (+)-coronarin A and congeners from (+)-sclareolide. | 2003 Jun 16 |
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| The nicholas approach to natural product hybrids. | 2006 Aug 16 |
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| (3aS,7S,9aS,9bR)-3a,6,6,9a-Tetra-methyl-2-oxoperhydro-naphtho[2,1-b]furan-7-yl acetate. | 2008 Aug 16 |
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| Differential enhancement of leukaemia cell differentiation without elevation of intracellular calcium by plant-derived sesquiterpene lactone compounds. | 2008 Nov |
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DSLD |
3501 (Number of products:2)
Created by
admin on Fri Dec 15 17:17:26 GMT 2023 , Edited by admin on Fri Dec 15 17:17:26 GMT 2023
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JECFA EVALUATION |
SCLAREOLIDE
Created by
admin on Fri Dec 15 17:17:26 GMT 2023 , Edited by admin on Fri Dec 15 17:17:26 GMT 2023
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1156
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37W4O0O6E6
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C109395
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SCLAREOLIDE
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1426934
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209-269-0
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DTXSID8047686
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37W4O0O6E6
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564-20-5
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929262
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PRIMARY |
SUBSTANCE RECORD
