Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C23H34O2 |
| Molecular Weight | 342.5149 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 4 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCC(=O)OC\C=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C
InChI
InChIKey=SFRPDSKECHTFQA-ONOWFSFQSA-N
InChI=1S/C23H34O2/c1-7-22(24)25-17-15-19(3)11-8-10-18(2)13-14-21-20(4)12-9-16-23(21,5)6/h8,10-11,13-15H,7,9,12,16-17H2,1-6H3/b11-8+,14-13+,18-10+,19-15+
Retinyl propionate is a synthetic derivative of a Vitamin A. Upon topical application, retinyl propionate is hydrolyzed by esterases to retinol, which is ultimately converted to retinoic acid. In mouse models, retinyl propionate induced epidermal thickening in mouse tail and promoted collagen formation in UV-irradiated mice. These results encouraged clinical trials of retinyl palmitate against photoaging. Topical retinyl propionate cream (0.15%) did not demonstrate any statistically significant improvement over placebo, but in later studies of combinations of retinyl propionate with climbazole or niacinamide improvements in the appearance of fine lines, wrinkles and age spots were demonstrated.
Approval Year
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| Code System | Code | Type | Description | ||
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C055385
Created by
admin on Fri Dec 15 19:43:08 GMT 2023 , Edited by admin on Fri Dec 15 19:43:08 GMT 2023
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1356759
Created by
admin on Fri Dec 15 19:43:08 GMT 2023 , Edited by admin on Fri Dec 15 19:43:08 GMT 2023
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7069-42-3
Created by
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230-363-2
Created by
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DTXSID701019851
Created by
admin on Fri Dec 15 19:43:08 GMT 2023 , Edited by admin on Fri Dec 15 19:43:08 GMT 2023
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32JK994WMC
Created by
admin on Fri Dec 15 19:43:08 GMT 2023 , Edited by admin on Fri Dec 15 19:43:08 GMT 2023
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RETINYL PROPIONATE
Created by
admin on Fri Dec 15 19:43:08 GMT 2023 , Edited by admin on Fri Dec 15 19:43:08 GMT 2023
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PRIMARY | Description: A yellow to brownish yellow, oily liquid. Solubility: Practically insoluble in water; soluble or partly soluble in dehydrated ethanol R; miscible with organic solvents. Category: Vitamin. Storage: The oily form of Retinol concentrate should be kept in a well-closed and well-filled container, protected from light. Oncethe container has been opened its contents should be used as soon as possible; any part of the contents not used at once should be protected by an atmosphere of inert gas. Labelling. The designation on the container should state the name of the retinol ester or esters, and their quantities expressed asthe content of vitamin A in International Units (IU) per gram, whether any stabilizing agents are added and their quantities, as well as the method of restoring the solution if partial crystallization has occurred. Additional information: Even in the absence of light the oily form of Retinol concentrate is gradually degraded on exposure to ahumid atmosphere, the decomposition being faster at higher temperatures. Partial crystallization may occur in concentrated solutions and upon refrigeration. | ||
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32JK994WMC
Created by
admin on Fri Dec 15 19:43:08 GMT 2023 , Edited by admin on Fri Dec 15 19:43:08 GMT 2023
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300000018733
Created by
admin on Fri Dec 15 19:43:08 GMT 2023 , Edited by admin on Fri Dec 15 19:43:08 GMT 2023
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6394572
Created by
admin on Fri Dec 15 19:43:08 GMT 2023 , Edited by admin on Fri Dec 15 19:43:08 GMT 2023
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SUBSTANCE RECORD
