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Details

Stereochemistry ACHIRAL
Molecular Formula C6H12Cl3O4P
Molecular Weight 285.49
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRIS(2-CHLOROETHYL)PHOSPHATE

SMILES

ClCCOP(=O)(OCCCl)OCCCl

InChI

InChIKey=HQUQLFOMPYWACS-UHFFFAOYSA-N
InChI=1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Metabolism of tris(2-chloroethyl) phosphate in rats and mice.
1991 Mar-Apr
NTP Toxicology and Carcinogenesis Studies of Tris(2-chloroethyl) Phosphate (CAS No. 115-96-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
1991 May
Chlorinated ethyl and isopropyl phosphoric acid triesters in the indoor environment--an inter-laboratory exposure study.
2001 Sep
Degradation of organophosphoric esters in leachate from a sea-based solid waste disposal site.
2002 Jul
Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance.
2002 Mar 15
Monitoring of the three organophosphate esters TBP, TCEP and TBEP in river water and ground water (Oder, Germany).
2003 Apr
Estimation of organophosphoric acid triesters in soft polyurethane foam using a concentrated sulfuric acid dissolution technique and gas chromatography with flame photometric detection.
2003 Dec
Screening of organophosphorus compounds and their distribution in various indoor environments.
2003 Dec
Organophosphate flame retardants and plasticisers in wastewater treatment plants.
2004 Jul
Exposure to phthalate esters from indoor environment.
2004 Nov
Organophosphorus flame retardants and plasticisers in surface waters.
2004 Oct 1
Organophosphorus flame retardants and plasticizers in air from various indoor environments.
2005 Aug
Organophosphate triesters in indoor environments.
2005 Sep
Elimination of organophosphate ester flame retardants and plasticizers in drinking water purification.
2006 Feb
Investigation of cytotoxic, genotoxic, mutagenic, and estrogenic effects of the flame retardants tris-(2-chloroethyl)-phosphate (TCEP) and tris-(2-chloropropyl)-phosphate (TCPP) in vitro.
2006 Feb 20
Determination of phosphoric acid triesters in human plasma using solid-phase microextraction and gas chromatography coupled to inductively coupled plasma mass spectrometry.
2006 Jan 27
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
2006 Nov
Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast.
2007
Indoor organophosphate and polybrominated flame retardants in Tokyo.
2007 Feb
[Evaluation of indoor air contaminants by means of reference and guideline values].
2007 Jul
Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters.
2007 Mar
[Determination of three organophosphorous flame retardants in textiles by gas chromatography].
2007 May
Differential response of Mono Mac 6, BEAS-2B, and Jurkat cells to indoor dust.
2007 Sep
Photooxidation and subsequent biodegradability of recalcitrant tri-alkyl phosphates TCEP and TBP in water.
2008 Dec
Effect of tris-(2-chloroethyl)-phosphate (TCEP) at environmental concentration on the levels of cell cycle regulatory protein expression in primary cultured rabbit renal proximal tubule cells.
2008 Dec
Enrichment and characterization of chlorinated organophosphate ester-degrading mixed bacterial cultures.
2008 Jul
Sources of endocrine-disrupting chemicals in urban wastewater, Oakland, CA.
2008 Nov 1
A national reconnaissance of pharmaceuticals and other organic wastewater contaminants in the United States--I) groundwater.
2008 Sep 1
A national reconnaissance for pharmaceuticals and other organic wastewater contaminants in the United States--II) untreated drinking water sources.
2008 Sep 1
Advanced oxidation kinetics of aqueous trialkyl phosphate flame retardants and plasticizers.
2009 Apr 15
Respiratory and dermal exposure to organophosphorus flame retardants and tetrabromobisphenol A at five work environments.
2009 Feb 1
Waste-indicator and pharmaceutical compounds in landfill-leachate-affected ground water near Elkhart, Indiana, 2000-2002.
2009 Jun
Indirect potable reuse: a sustainable water supply alternative.
2009 Mar
Cellular effect evaluation of micropollutants using transporter functions of renal proximal tubule cells.
2009 Nov
Pressurized liquid extraction of organophosphate triesters from sediment samples using aqueous solutions.
2009 Oct 16
Intra- and interspecific nuclear ribosomal gene variation in the two Japanese Eothenomys species, E. andersoni and E. smithii.
2010 Dec
Organophosphate ester flame retardant-induced acute intoxications in dogs.
2010 Dec
Seasonal fluctuations of organophosphate concentrations in precipitation and storm water runoff.
2010 Feb
Occurrence and fate of organophosphorus flame retardants and plasticizers in urban and remote surface waters in Germany.
2010 Jul
Human health risk assessment of pharmaceuticals in water: issues and challenges ahead.
2010 Nov
Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish.
2012 Jun 15
Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays.
2013 Mar 19
Toxicity of TDCPP and TCEP on PC12 cell: changes in CAMKII, GAP43, tubulin and NF-H gene and protein levels.
2014 Jun 16
Potential estrogenic effects of phosphorus-containing flame retardants.
2014 Jun 17
Determination and prediction of the binding interaction between organophosphate flame retardants and p53.
2014 Nov 17
Affinities of organophosphate flame retardants to tumor suppressor gene p53: an integrated in vitro and in silico study.
2015 Jan 22
TPP and TCEP induce oxidative stress and alter steroidogenesis in TM3 Leydig cells.
2015 Nov
Patents
Name Type Language
TRIS(2-CHLOROETHYL)PHOSPHATE
Systematic Name English
PHOSPHORIC ACID, TRIS(2-CHLOROETHYL) ESTER
Common Name English
TRIS(2-CHLOROETHYL) PHOSPHATE [IARC]
Common Name English
TRIS(2-CHLOROETHYL) PHOSPHATE [HSDB]
Common Name English
TRIS(2-CHLOROETHYL) PHOSPHATE
HSDB  
Systematic Name English
TRI(.BETA.-CHLOROETHYL) PHOSPHATE
Systematic Name English
NSC-3213
Code English
ETHANOL, 2-CHLORO-, PHOSPHATE (3:1)
Systematic Name English
Code System Code Type Description
CHEBI
35037
Created by admin on Fri Dec 15 17:32:47 GMT 2023 , Edited by admin on Fri Dec 15 17:32:47 GMT 2023
PRIMARY
FDA UNII
32IVO568B0
Created by admin on Fri Dec 15 17:32:47 GMT 2023 , Edited by admin on Fri Dec 15 17:32:47 GMT 2023
PRIMARY
EPA CompTox
DTXSID5021411
Created by admin on Fri Dec 15 17:32:47 GMT 2023 , Edited by admin on Fri Dec 15 17:32:47 GMT 2023
PRIMARY
PUBCHEM
8295
Created by admin on Fri Dec 15 17:32:47 GMT 2023 , Edited by admin on Fri Dec 15 17:32:47 GMT 2023
PRIMARY
WIKIPEDIA
TRIS(2-CHLOROETHYL) PHOSPHATE
Created by admin on Fri Dec 15 17:32:47 GMT 2023 , Edited by admin on Fri Dec 15 17:32:47 GMT 2023
PRIMARY
NSC
3213
Created by admin on Fri Dec 15 17:32:47 GMT 2023 , Edited by admin on Fri Dec 15 17:32:47 GMT 2023
PRIMARY
CAS
115-96-8
Created by admin on Fri Dec 15 17:32:47 GMT 2023 , Edited by admin on Fri Dec 15 17:32:47 GMT 2023
PRIMARY
HSDB
2577
Created by admin on Fri Dec 15 17:32:47 GMT 2023 , Edited by admin on Fri Dec 15 17:32:47 GMT 2023
PRIMARY
ECHA (EC/EINECS)
204-118-5
Created by admin on Fri Dec 15 17:32:47 GMT 2023 , Edited by admin on Fri Dec 15 17:32:47 GMT 2023
PRIMARY