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Details

Stereochemistry ACHIRAL
Molecular Formula C6H12Cl3O4P
Molecular Weight 285.49
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRIS(2-CHLOROETHYL)PHOSPHATE

SMILES

ClCCOP(=O)(OCCCl)OCCCl

InChI

InChIKey=HQUQLFOMPYWACS-UHFFFAOYSA-N
InChI=1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
TPP and TCEP induce oxidative stress and alter steroidogenesis in TM3 Leydig cells.
2015-11
Affinities of organophosphate flame retardants to tumor suppressor gene p53: an integrated in vitro and in silico study.
2015-01-22
Determination and prediction of the binding interaction between organophosphate flame retardants and p53.
2014-11-17
Potential estrogenic effects of phosphorus-containing flame retardants.
2014-06-17
Toxicity of TDCPP and TCEP on PC12 cell: changes in CAMKII, GAP43, tubulin and NF-H gene and protein levels.
2014-06-16
Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays.
2013-03-19
Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish.
2012-06-15
Intra- and interspecific nuclear ribosomal gene variation in the two Japanese Eothenomys species, E. andersoni and E. smithii.
2010-12
Organophosphate ester flame retardant-induced acute intoxications in dogs.
2010-12
Human health risk assessment of pharmaceuticals in water: issues and challenges ahead.
2010-11
Occurrence and fate of organophosphorus flame retardants and plasticizers in urban and remote surface waters in Germany.
2010-07
Seasonal fluctuations of organophosphate concentrations in precipitation and storm water runoff.
2010-02
Cellular effect evaluation of micropollutants using transporter functions of renal proximal tubule cells.
2009-11
Pressurized liquid extraction of organophosphate triesters from sediment samples using aqueous solutions.
2009-10-16
Waste-indicator and pharmaceutical compounds in landfill-leachate-affected ground water near Elkhart, Indiana, 2000-2002.
2009-06
Advanced oxidation kinetics of aqueous trialkyl phosphate flame retardants and plasticizers.
2009-04-15
Indirect potable reuse: a sustainable water supply alternative.
2009-03
Respiratory and dermal exposure to organophosphorus flame retardants and tetrabromobisphenol A at five work environments.
2009-02-01
Photooxidation and subsequent biodegradability of recalcitrant tri-alkyl phosphates TCEP and TBP in water.
2008-12
Effect of tris-(2-chloroethyl)-phosphate (TCEP) at environmental concentration on the levels of cell cycle regulatory protein expression in primary cultured rabbit renal proximal tubule cells.
2008-12
Sources of endocrine-disrupting chemicals in urban wastewater, Oakland, CA.
2008-11-01
A national reconnaissance of pharmaceuticals and other organic wastewater contaminants in the United States--I) groundwater.
2008-09-01
A national reconnaissance for pharmaceuticals and other organic wastewater contaminants in the United States--II) untreated drinking water sources.
2008-09-01
Enrichment and characterization of chlorinated organophosphate ester-degrading mixed bacterial cultures.
2008-07
Differential response of Mono Mac 6, BEAS-2B, and Jurkat cells to indoor dust.
2007-09
[Evaluation of indoor air contaminants by means of reference and guideline values].
2007-07
[Determination of three organophosphorous flame retardants in textiles by gas chromatography].
2007-05
Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters.
2007-03
Indoor organophosphate and polybrominated flame retardants in Tokyo.
2007-02
Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast.
2007
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
2006-11
Investigation of cytotoxic, genotoxic, mutagenic, and estrogenic effects of the flame retardants tris-(2-chloroethyl)-phosphate (TCEP) and tris-(2-chloropropyl)-phosphate (TCPP) in vitro.
2006-02-20
Elimination of organophosphate ester flame retardants and plasticizers in drinking water purification.
2006-02
Determination of phosphoric acid triesters in human plasma using solid-phase microextraction and gas chromatography coupled to inductively coupled plasma mass spectrometry.
2006-01-27
Organophosphate triesters in indoor environments.
2005-09
Organophosphorus flame retardants and plasticizers in air from various indoor environments.
2005-08
Exposure to phthalate esters from indoor environment.
2004-11
Organophosphorus flame retardants and plasticisers in surface waters.
2004-10-01
Organophosphate flame retardants and plasticisers in wastewater treatment plants.
2004-07
Estimation of organophosphoric acid triesters in soft polyurethane foam using a concentrated sulfuric acid dissolution technique and gas chromatography with flame photometric detection.
2003-12
Screening of organophosphorus compounds and their distribution in various indoor environments.
2003-12
Monitoring of the three organophosphate esters TBP, TCEP and TBEP in river water and ground water (Oder, Germany).
2003-04
Degradation of organophosphoric esters in leachate from a sea-based solid waste disposal site.
2002-07
Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance.
2002-03-15
Chlorinated ethyl and isopropyl phosphoric acid triesters in the indoor environment--an inter-laboratory exposure study.
2001-09
NTP Toxicology and Carcinogenesis Studies of Tris(2-chloroethyl) Phosphate (CAS No. 115-96-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
1991-05
Metabolism of tris(2-chloroethyl) phosphate in rats and mice.
1991-03-01
Patents
Name Type Language
TRIS(2-CHLOROETHYL)PHOSPHATE
Systematic Name English
TRIS(2-CHLOROETHYL) PHOSPHATE
HSDB  
Preferred Name English
PHOSPHORIC ACID, TRIS(2-CHLOROETHYL) ESTER
Common Name English
TRIS(2-CHLOROETHYL) PHOSPHATE [IARC]
Common Name English
TRIS(2-CHLOROETHYL) PHOSPHATE [HSDB]
Common Name English
TRI(.BETA.-CHLOROETHYL) PHOSPHATE
Systematic Name English
NSC-3213
Code English
ETHANOL, 2-CHLORO-, PHOSPHATE (3:1)
Systematic Name English
Code System Code Type Description
CHEBI
35037
Created by admin on Mon Mar 31 18:48:03 GMT 2025 , Edited by admin on Mon Mar 31 18:48:03 GMT 2025
PRIMARY
FDA UNII
32IVO568B0
Created by admin on Mon Mar 31 18:48:03 GMT 2025 , Edited by admin on Mon Mar 31 18:48:03 GMT 2025
PRIMARY
EPA CompTox
DTXSID5021411
Created by admin on Mon Mar 31 18:48:03 GMT 2025 , Edited by admin on Mon Mar 31 18:48:03 GMT 2025
PRIMARY
PUBCHEM
8295
Created by admin on Mon Mar 31 18:48:03 GMT 2025 , Edited by admin on Mon Mar 31 18:48:03 GMT 2025
PRIMARY
WIKIPEDIA
TRIS(2-CHLOROETHYL) PHOSPHATE
Created by admin on Mon Mar 31 18:48:03 GMT 2025 , Edited by admin on Mon Mar 31 18:48:03 GMT 2025
PRIMARY
NSC
3213
Created by admin on Mon Mar 31 18:48:03 GMT 2025 , Edited by admin on Mon Mar 31 18:48:03 GMT 2025
PRIMARY
SMS_ID
300000053674
Created by admin on Mon Mar 31 18:48:03 GMT 2025 , Edited by admin on Mon Mar 31 18:48:03 GMT 2025
PRIMARY
CAS
115-96-8
Created by admin on Mon Mar 31 18:48:03 GMT 2025 , Edited by admin on Mon Mar 31 18:48:03 GMT 2025
PRIMARY
HSDB
2577
Created by admin on Mon Mar 31 18:48:03 GMT 2025 , Edited by admin on Mon Mar 31 18:48:03 GMT 2025
PRIMARY
ECHA (EC/EINECS)
204-118-5
Created by admin on Mon Mar 31 18:48:03 GMT 2025 , Edited by admin on Mon Mar 31 18:48:03 GMT 2025
PRIMARY