NANOFIN

Details

Stereochemistry	UNKNOWN
Molecular Formula	C7H15N
Molecular Weight	113.2007
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1CCCC(C)N1

InChI

InChIKey=SDGKUVSVPIIUCF-UHFFFAOYSA-N

InChI=1S/C7H15N/c1-6-4-3-5-7(2)8-6/h6-8H,3-5H2,1-2H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13506810 | https://www.ncbi.nlm.nih.gov/pubmed/13580555 https://www.selleck.co.jp/products/nanofin.html

Nanofin is a ganglion blocker alkaloid having nicotinic acetylcholine receptor antagonist action. It has an antihypertensive effect used for mild to moderate hypertension. It was also used for the treatment of eczema and neurodermatitis.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Nicotinic acetylcholine receptor 10 Target ID: Nicotinic acetylcholine receptor Sources: https://www.selleck.co.jp/products/nanofin.html	Antagonist 2849

PubMed

Title	Date	PubMed
Active site directed docking studies: synthesis and pharmacological evaluation of cis-2,6-dimethyl piperidine sulfonamides as inhibitors of acetylcholinesterase.	2009-10	19493592
Combined experimental and computational study of the thermochemistry of methylpiperidines.	2006-05-12	16674037
Development of an efficient strategy for the synthesis of the ETB receptor antagonist BQ-788 and some related analogues.	2005-08	16042984
Mechanism of hydrodenitrogenation on phosphides and sulfides.	2005-02-17	16851202

Patents

Name

Type

Language

NSC-63890

Preferred Name

English

NANOFIN

Official Name

English

nanofin [INN]

Common Name

English

2,6-LUPETIDINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66886