Corticorelin (Xerecept) is a synthetic analog of the naturally occurring human peptide corticotropin-releasing factor (CRF). Corticotropin-releasing factor is the predominant regulator of adrenocorticotropic-hormone (ACTH) formation and release by the pituitary. In addition to its primary location in the hypothalamic paraventricular nucleus, endogenous CRF has also been identified in cerebral cortical interneurons, the limbic system, brain stem and spinal cord. Several studies have indicated the ability of CRF to reduce the brain edema caused by brain tumors. Clinical trials with the Corticorelin (Xerecept) have indicated that this drug has a distinct advantage over classical corticosteroids in the treatment of brain edema. Fewer and/or milder side effects have been reported for corticorelin compared with dexamethasone, although at higher doses of corticorelin several side effects, including hypotension and transient flushing, have been reported.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://clinicaltrials.gov/ct2/show/NCT00226668
2mg/day
Route of Administration:
Other
Name | Type | Language | ||
---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
WHO-VATC |
QV04CD04
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
||
|
FDA ORPHAN DRUG |
108097
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
||
|
WHO-ATC |
V04CD04
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
DB05394
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
SUB27540
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
m3845
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
9015-71-8
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
GENERIC (FAMILY) | |||
|
CORTICORELIN
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
1927940
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
305OE8862Y
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
C394
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
305OE8862Y
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
86784-80-7
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
65312
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
6666
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
D003346
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
214461
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
ALTERNATIVE | RxNorm | ||
|
4858
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
16186200
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
65311
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
CHEMBL2108182
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
100000090514
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
DTXSID70235807
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY | |||
|
SUB13468MIG
Created by
admin on Fri Dec 15 16:22:27 GMT 2023 , Edited by admin on Fri Dec 15 16:22:27 GMT 2023
|
PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)