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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H13FN2O4
Molecular Weight 243.2222
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALOVUDINE F-18

SMILES

CC1=CN([C@H]2C[C@H]([18F])[C@@H](CO)O2)C(=O)NC1=O

InChI

InChIKey=UXCAQJAQSWSNPQ-ZIVQXEJRSA-N
InChI=1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1/i11-1

HIDE SMILES / InChI
3'-[(18)F]fluoro-3'-deoxythymidine [[(18)F]-FLT or ALOVUDINE F-18], a tracer for positron emission tomography (PET) that is used for imaging of proliferation in human malignant lymphoma. This compound is also useful for making a proper diagnosis and monitoring treatment response of aplastic anemia patients, because can show overview of the bone marrow compartment in aplastic anemia.

Approval Year

PubMed

PubMed

TitleDatePubMed
F-18 FLT PET: a noninvasive diagnostic tool for visualization of the bone marrow compartment in patients with aplastic anemia: a pilot study.
2011 Apr
Imaging bone-marrow activity with (18)F-fluorothymidine PET.
2018 Jan
Correlation between tumour biology status measured in triple-tracer 18F-fluorodeoxyglucose-18F-fluorothymidine- 18F-fluoromisonidazole-PET/CT study and human papillomavirus status in patients with head and neck cancer.
2019 Jul
Name Type Language
ALOVUDINE F-18
Common Name English
18F-FLT
Common Name English
(F-18)FLT
Common Name English
(18F)FLT
Common Name English
THYMIDINE, 3'-DEOXY-3'-(18F)FLUORO-
Common Name English
3'-DEOXY-3'-(18F)FLUOROTHYMIDINE
Common Name English
FLUOROTHYMIDINE F-18
Common Name English
Fluorothymidine (18F) [WHO-DD]
Common Name English
(18F) FLT
Common Name English
FLT F-18
Common Name English
(18F)-FLT
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C2124
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
Code System Code Type Description
DRUG BANK
DB14930
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
PRIMARY
MESH
C002854
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
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NCI_THESAURUS
C49093
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
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PUBCHEM
9878109
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
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SMS_ID
100000127601
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
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FDA UNII
2X1K91UT6N
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
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EPA CompTox
DTXSID90182869
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
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CAS
287114-80-1
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
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WIKIPEDIA
Fluorothymidine F-18
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
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EVMPD
SUB33646
Created by admin on Fri Dec 15 15:40:54 GMT 2023 , Edited by admin on Fri Dec 15 15:40:54 GMT 2023
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