U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C27H30N2O6S
Molecular Weight 510.602
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TOBICILLIN

SMILES

[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)CC3=CC=CC=C3)C(=O)OC4=CC(COC(=O)C(C)C)=CC=C4

InChI

InChIKey=MGKUHWMKIYHWOJ-AOHZBQACSA-N
InChI=1S/C27H30N2O6S/c1-16(2)25(32)34-15-18-11-8-12-19(13-18)35-26(33)22-27(3,4)36-24-21(23(31)29(22)24)28-20(30)14-17-9-6-5-7-10-17/h5-13,16,21-22,24H,14-15H2,1-4H3,(H,28,30)/t21-,22+,24-/m1/s1

HIDE SMILES / InChI

Description
Curator's Comment: Description was created, based on several sources, including https://www.jstage.jst.go.jp/article/fishsci1994/63/5/63_5_741/_pdf

Tobicillin (TBPC) is an ester derivative of penicillin G. It is a beta-Lactam antibiotic, peptidoglycan biosynthesis inhibitor. TBPC was shown to be the effective antibiotic for the treatment of enterococcicosis in yellowtail.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Unknown

Approved Use

Unknown
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
MIC90 of Tobicillin against E. seriolicida - >/=100ug/ml
Name Type Language
TOBICILLIN
INN   JAN  
INN  
Official Name English
tobicillin [INN]
Common Name English
TOBICILLIN [JAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1500
Created by admin on Fri Dec 15 15:43:25 GMT 2023 , Edited by admin on Fri Dec 15 15:43:25 GMT 2023
Code System Code Type Description
FDA UNII
2P43Z53ESB
Created by admin on Fri Dec 15 15:43:25 GMT 2023 , Edited by admin on Fri Dec 15 15:43:25 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105430
Created by admin on Fri Dec 15 15:43:25 GMT 2023 , Edited by admin on Fri Dec 15 15:43:25 GMT 2023
PRIMARY
INN
7660
Created by admin on Fri Dec 15 15:43:25 GMT 2023 , Edited by admin on Fri Dec 15 15:43:25 GMT 2023
PRIMARY
SMS_ID
100000082144
Created by admin on Fri Dec 15 15:43:25 GMT 2023 , Edited by admin on Fri Dec 15 15:43:25 GMT 2023
PRIMARY
EPA CompTox
DTXSID3057648
Created by admin on Fri Dec 15 15:43:25 GMT 2023 , Edited by admin on Fri Dec 15 15:43:25 GMT 2023
PRIMARY
CAS
151287-22-8
Created by admin on Fri Dec 15 15:43:25 GMT 2023 , Edited by admin on Fri Dec 15 15:43:25 GMT 2023
PRIMARY
PUBCHEM
216265
Created by admin on Fri Dec 15 15:43:25 GMT 2023 , Edited by admin on Fri Dec 15 15:43:25 GMT 2023
PRIMARY
NCI_THESAURUS
C76861
Created by admin on Fri Dec 15 15:43:25 GMT 2023 , Edited by admin on Fri Dec 15 15:43:25 GMT 2023
PRIMARY
EVMPD
SUB11132MIG
Created by admin on Fri Dec 15 15:43:25 GMT 2023 , Edited by admin on Fri Dec 15 15:43:25 GMT 2023
PRIMARY