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Details

Stereochemistry RACEMIC
Molecular Formula C17H25NO
Molecular Weight 259.3865
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EPERISONE

SMILES

CCC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2

InChI

InChIKey=SQUNAWUMZGQQJD-UHFFFAOYSA-N
InChI=1S/C17H25NO/c1-3-15-7-9-16(10-8-15)17(19)14(2)13-18-11-5-4-6-12-18/h7-10,14H,3-6,11-13H2,1-2H3

HIDE SMILES / InChI

Description

Eperisone is an antispasmodic drug approved in Japan for the treatment of of diseases characterized by muscle stiffness and pain. It is believed that eperisone exerts its effect through inhibition of sodium channels. The drug is still being marketed in Asia under the name Myonal (Square Pharmaceuticals).

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
MYONAL
Palliative
MYONAL
Palliative
MYONAL
Palliative
MYONAL

PubMed

Sample Use Guides

In Vivo Use Guide
150 mg of eperisone hydrochloride daily in three divided doses after meals
Route of Administration: Oral
In Vitro Use Guide
Eperisone (25–200 uM) depressed the ventral root potential of isolated hemisected spinal cord of 6-day-old rats.