PICEIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C14H18O7
Molecular Weight	298.2885
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)C1=CC=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C1

InChI

InChIKey=GOZCEKPKECLKNO-RKQHYHRCSA-N

InChI=1S/C14H18O7/c1-7(16)8-2-4-9(5-3-8)20-14-13(19)12(18)11(17)10(6-15)21-14/h2-5,10-15,17-19H,6H2,1H3/t10-,11-,12+,13-,14-/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/21647585 | https://www.ncbi.nlm.nih.gov/pubmed/26307962

Picein is a phenolic compound from mycorrhizal roots of Norway spruces (Picea abies). Picein moderately promoted adipogenesis of 3T3-L1 cells. Picein has being shown to be active against the rat small intestinal α-glucosidase.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
triglyceride metabolic process 1 Target ID: GO:0006641 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21647585	Modulator 828
Acidic alpha-glucosidase 3 Target ID: CHEMBL3513 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26307962	Inhibitor 8297		10.68 mM [IC50]

Conditions

Condition	Modality	Targets	Highest Phase	Product
Type 2 diabetes mellitus 259 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26307962	Primary		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

3 uM of picein caused 11.3% increase in TG levels in 3T3-L1 cells

Name

Type

Language

PICEIN

Common Name

English

SALINIGRIN

Common Name

English

PICEOSIDE

Common Name

English

PICEIN [MI]

Common Name

English

SALICINEREIN

Common Name

English

4-ACETYLPHENYL .BETA.-D-GLUCOPYRANOSIDE

Systematic Name

English

ETHANONE, 1-(4-(.BETA.-D-GLUCOPYRANOSYLOXY)PHENYL)-

Systematic Name

English

P-HYDROXYACETOPHENONE-D-GLUCOSIDE

Systematic Name

English

AMELIAROSIDE

Common Name

English

Code System Code Type Description

PUBCHEM

92123