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Details

Stereochemistry ABSOLUTE
Molecular Formula C14H18O7
Molecular Weight 298.2885
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PICEIN

SMILES

CC(=O)C1=CC=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C1

InChI

InChIKey=GOZCEKPKECLKNO-RKQHYHRCSA-N
InChI=1S/C14H18O7/c1-7(16)8-2-4-9(5-3-8)20-14-13(19)12(18)11(17)10(6-15)21-14/h2-5,10-15,17-19H,6H2,1H3/t10-,11-,12+,13-,14-/m1/s1

HIDE SMILES / InChI

Description

Picein is a phenolic compound from mycorrhizal roots of Norway spruces (Picea abies). Picein moderately promoted adipogenesis of 3T3-L1 cells. Picein has being shown to be active against the rat small intestinal α-glucosidase.

Approval Year

Unknown
149,124

Targets

Primary TargetPharmacologyConditionPotency
triglyceride metabolic process
1
Modulator
846
Acidic alpha-glucosidase
3
Inhibitor
8,504
 10.68 mM [IC50]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Type 2 diabetes mellitus
262
 Primary
Basic research
Unknown

PubMed

Patents

US2008118589
1
US2015232889
1
US8105786
1

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
3 uM of picein caused 11.3% increase in TG levels in 3T3-L1 cells
SUBSTANCE RECORD
Structure of PICEIN
NIH
NCATS
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