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Details

Stereochemistry ACHIRAL
Molecular Formula C19H16ClFN2O
Molecular Weight 342.7952
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUTOPRAZEPAM

SMILES

c1ccc(c(c1)C2=NCC(=O)N(CC3CC3)c4ccc(cc42)Cl)F

InChI

InChIKey=OFVXPDXXVSGEPX-UHFFFAOYSA-N
InChI=1S/C19H16ClFN2O/c20-13-7-8-17-15(9-13)19(14-3-1-2-4-16(14)21)22-10-18(24)23(17)11-12-5-6-12/h1-4,7-9,12H,5-6,10-11H2

HIDE SMILES / InChI

Description
Curator's Comment:: description was created based on several sources, including, http://www.ncbi.nlm.nih.gov/pubmed/6148044

Flutoprazepam is a benzodiazepine derivative that reduce anxiety, stress, depression, fatigability and sleep disorders in patients with neurosis and psychosomatic disorders by binding to GABA-A receptor and modulating its activity.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
RESTAS

Approved Use

It is usually used for the improvement of anxiety, stress and depression; fatigability; and sleep disorder associated with neurosis and psychosomatic disorder (hypertension, gastric and duodenal ulcer, chronic gastritis, irritable bowel syndrome), and psychosomatic symptoms.
Primary
RESTAS

Approved Use

It is usually used for the improvement of anxiety, stress and depression; fatigability; and sleep disorder associated with neurosis and psychosomatic disorder (hypertension, gastric and duodenal ulcer, chronic gastritis, irritable bowel syndrome), and psychosomatic symptoms.
Primary
RESTAS

Approved Use

It is usually used for the improvement of anxiety, stress and depression; fatigability; and sleep disorder associated with neurosis and psychosomatic disorder (hypertension, gastric and duodenal ulcer, chronic gastritis, irritable bowel syndrome), and psychosomatic symptoms.
PubMed

PubMed

TitleDatePubMed
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
2010 Dec
Patents

Patents

Sample Use Guides

For adults, take 1 to 2 tablets (2 to 4 mg of the active ingredient) in 1 to 2 divided doses daily.
Route of Administration: Oral
Name Type Language
FLUTOPRAZEPAM
INN   JAN   MART.   MI   WHO-DD  
INN  
Official Name English
FLUTOPRAZEPAM [WHO-DD]
Common Name English
RESTAS
Brand Name English
FLUTOPRAZEPAM [MART.]
Common Name English
7-CHLORO-1-(CYCLOPROPYLMETHYL)-5-(O-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE
Common Name English
FLUTOPRAZEPAM [JAN]
Common Name English
FLUTOPRAZEPAM [MI]
Common Name English
FLUTOPRAZEPAM [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1012
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
NCI_THESAURUS C264
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
Code System Code Type Description
WIKIPEDIA
FLUTOPRAZEPAM
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY
MESH
C029163
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY
MERCK INDEX
M1172
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY Merck Index
EVMPD
SUB07764MIG
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY
EPA CompTox
25967-29-7
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY
FDA UNII
2GHY1101MM
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY
CAS
25967-29-7
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY
PUBCHEM
3400
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY
ChEMBL
CHEMBL2106743
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY
INN
5037
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY
DRUG CENTRAL
1226
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY
NCI_THESAURUS
C65742
Created by admin on Fri Jun 25 21:33:57 UTC 2021 , Edited by admin on Fri Jun 25 21:33:57 UTC 2021
PRIMARY