Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C5H4FN5 |
| Molecular Weight | 153.1172 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=C2NC=NC2=NC(F)=N1
InChI
InChIKey=WKMPTBDYDNUJLF-UHFFFAOYSA-N
InChI=1S/C5H4FN5/c6-5-10-3(7)2-4(11-5)9-1-8-2/h1H,(H3,7,8,9,10,11)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells. | 2001 Feb |
|
| Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models. | 2002 Jun |
|
| Synthesis of 2',5'-dideoxy-2-fluoroadenosine and 2',5'-dideoxy-2,5'-difluoroadenosine: potent P-site inhibitors of adenylyl cyclase. | 2004 Feb 26 |
|
| Preclinical evaluation of a prostate-targeted gene-directed enzyme prodrug therapy delivered by ovine atadenovirus. | 2004 Nov |
|
| Enzymatic synthesis and 19F NMR studies of 2-fluoroadenine-substituted RNA. | 2004 Sep 29 |
|
| Oligotide, a defibrotide derivative, protects human microvascular endothelial cells against fludarabine-induced activation, damage and allogenicity. | 2005 May |
|
| Nicotinamide 2-fluoroadenine dinucleotide unmasks the NAD+ glycohydrolase activity of Aplysia californica adenosine 5'-diphosphate ribosyl cyclase. | 2007 Apr 3 |
|
| Characterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPT. | 2009 Dec 3 |
|
| Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine. | 2009 May |
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C45176
Created by
admin on Sat Dec 16 05:14:42 GMT 2023 , Edited by admin on Sat Dec 16 05:14:42 GMT 2023
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NCI_THESAURUS |
C45183
Created by
admin on Sat Dec 16 05:14:42 GMT 2023 , Edited by admin on Sat Dec 16 05:14:42 GMT 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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72457
Created by
admin on Sat Dec 16 05:14:42 GMT 2023 , Edited by admin on Sat Dec 16 05:14:42 GMT 2023
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PRIMARY | |||
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C29794
Created by
admin on Sat Dec 16 05:14:42 GMT 2023 , Edited by admin on Sat Dec 16 05:14:42 GMT 2023
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2C8H3H4EBG
Created by
admin on Sat Dec 16 05:14:42 GMT 2023 , Edited by admin on Sat Dec 16 05:14:42 GMT 2023
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700-49-2
Created by
admin on Sat Dec 16 05:14:42 GMT 2023 , Edited by admin on Sat Dec 16 05:14:42 GMT 2023
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DTXSID80220264
Created by
admin on Sat Dec 16 05:14:42 GMT 2023 , Edited by admin on Sat Dec 16 05:14:42 GMT 2023
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27364
Created by
admin on Sat Dec 16 05:14:42 GMT 2023 , Edited by admin on Sat Dec 16 05:14:42 GMT 2023
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12790
Created by
admin on Sat Dec 16 05:14:42 GMT 2023 , Edited by admin on Sat Dec 16 05:14:42 GMT 2023
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PRIMARY |
SUBSTANCE RECORD
