LITRACEN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H23N
Molecular Weight	277.4033
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNCCC=C1C2=CC=CC=C2C(C)(C)C3=C1C=CC=C3

InChI

InChIKey=AUZMDLDJTGPIEA-UHFFFAOYSA-N

InChI=1S/C20H23N/c1-20(2)18-12-6-4-9-16(18)15(11-8-14-21-3)17-10-5-7-13-19(17)20/h4-7,9-13,21H,8,14H2,1-3H3

HIDE SMILES / InChI

Description
Sources: Psychopharmacology Abstracts, v.6, #1, page 265, retrieved from: https://books.google.ru/books?id=XXLdSngjyOgC | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 736, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Litracen revealed very potent thymoleptic properties with a weak sedative action. Melitracen is gradually metabolized to litracen, and after repeated doses of melitracen, the organs will, for the most part, contain the metabolite. Litracen was developed as an antidepressant agent.

Approval Year

PubMed

Title	Date	PubMed
The distribution pattern of a series of tricyclic and bicyclic thymoleptics compared with their lipophilic properties and binding to plasma proteins.	1973	4800688
The pharmacological properties of melitracen (N 7001) and litracen (N 7049).	1966-02	6014004

Name

Type

Language

litracen [INN]

Preferred Name

English

LITRACEN

Official Name

English

9-(3-METHYLAMINOPROPYLIDENE)-10,10-DIMETHYL-9,10-DIHYDROANTHRACENE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265