Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H5Cl5 |
| Molecular Weight | 326.433 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC=C(C=C1Cl)C2=CC(Cl)=C(Cl)C=C2Cl
InChI
InChIKey=IUTPYMGCWINGEY-UHFFFAOYSA-N
InChI=1S/C12H5Cl5/c13-8-2-1-6(3-10(8)15)7-4-11(16)12(17)5-9(7)14/h1-5H
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample. | 2015-07 |
|
| Consensus toxicity factors for polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls combining in silico models and extensive in vitro screening of AhR-mediated effects in human and rodent cells. | 2015-04-20 |
|
| Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. | 2015-04-01 |
|
| Comparison of intake and systemic relative effect potencies of dioxin-like compounds in female mice after a single oral dose. | 2013-07 |
|
| Cytochrome P4501A induction in avian hepatocyte cultures exposed to polychlorinated biphenyls: comparisons with AHR1-mediated reporter gene activity and in ovo toxicity. | 2013-01-01 |
|
| Lipopolysaccharide potentiates polychlorinated biphenyl-induced disruption of the blood-brain barrier via TLR4/IRF-3 signaling. | 2012-12-16 |
|
| Proinflammatory adhesion molecules facilitate polychlorinated biphenyl-mediated enhancement of brain metastasis formation. | 2012-04 |
|
| Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO₂-PCBs. | 2011-10-10 |
|
| In utero and lactational exposure to PCBs in mice: adult offspring show altered learning and memory depending on Cyp1a2 and Ahr genotypes. | 2011-09 |
|
| In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans. | 2011-05 |
|
| In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes. | 2011-01 |
|
| Polychlorinated biphenyls, lead, and mercury are associated with liver disease in American adults: NHANES 2003-2004. | 2010-12 |
|
| Thyroid follicular lesions induced by oral treatment for 2 years with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds in female Harlan Sprague-Dawley rats. | 2010-12 |
|
| Highly purified hexachlorobenzene induces cytochrome P4501A in primary cultures of chicken embryo hepatocytes. | 2010-11-01 |
|
| Toxicology and carcinogenesis studies of 2,3',4,4',5-pentachlorobiphenyl (PCB 118) (CAS No. 31508-00-6) in female harlan Sprague-Dawley rats (gavage studies). | 2010-11 |
|
| DDE in mothers' blood during pregnancy and lower respiratory tract infections in their infants. | 2010-09 |
|
| Differential effects of polychlorinated biphenyl congeners on serum thyroid hormone levels in rats. | 2010-09 |
|
| Distribution of PCB 118 and PCB 153 and hydroxylated PCB metabolites (OH-CBs) in maternal, fetal and lamb tissues of sheep exposed during gestation and lactation. | 2010-08 |
|
| Polychlorinated biphenyls disrupt intestinal integrity via NADPH oxidase-induced alterations of tight junction protein expression. | 2010-07 |
|
| Polychlorinated biphenyls disrupt blood-brain barrier integrity and promote brain metastasis formation. | 2010-04 |
|
| Effects on bone tissue in ewes (Ovies aries) and their foetuses exposed to PCB 118 and PCB 153. | 2010-02-01 |
|
| Three structurally different polychlorinated biphenyl congeners (Pcb 118, 153, and 126) affect hormone production and gene expression in the human H295R in vitro model. | 2010 |
|
| Proteomic analysis during larval development and metamorphosis of the spionid polychaete Pseudopolydora vexillosa. | 2009-12-14 |
|
| Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells. | 2009-12-10 |
|
| Reproductive lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin and dioxin-like compounds. | 2009-12 |
|
| WITHDRAWN: Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity in a birth cohort. | 2009-07-30 |
|
| Cell death mechanisms in GT1-7 GnRH cells exposed to polychlorinated biphenyls PCB74, PCB118, and PCB153. | 2009-06-01 |
|
| Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population. | 2009-04 |
|
| Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition. | 2008-12 |
|
| Association of organochlorine pesticides with peripheral neuropathy in patients with diabetes or impaired fasting glucose. | 2008-11 |
|
| Serum concentrations of indicator PCB congeners in the Czech adult population. | 2008-07 |
|
| Different effects of PCB101, PCB118, PCB138 and PCB153 alone or mixed in MCF-7 breast cancer cells. | 2008-07 |
|
| Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood and breast milk collected from 60 mothers in Sapporo City, Japan. | 2008-07 |
|
| Biosensor immunoassay for the screening of dioxin-like polychlorinated biphenyls in retail fish. | 2008-06-09 |
|
| PCB 118 and Aryl Hydrocarbon Receptor Immunoassays for Screening Dioxins in Retail Fish. | 2008-05-14 |
|
| Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. | 2008-04 |
|
| Relative potency based on hepatic enzyme induction predicts immunosuppressive effects of a mixture of PCDDS/PCDFS and PCBS. | 2008-03-15 |
|
| Chemical and bioassay monitoring of PCB-contaminated soil remediation using solvent extraction technology. | 2008-02 |
|
| Polychlorinated biphenyls 105 and 118 form thyroid hormone receptor agonists after cytochrome P4501A1 activation in rat pituitary GH3 cells. | 2007-11 |
|
| Pathways and products of the degradation of PCBs by the sodium dispersion method. | 2007-06 |
|
| Dehalogenation of polychlorinated biphenyls and polybrominated diphenyl ethers using a hybrid bioinorganic catalyst. | 2007-04 |
|
| Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls. | 2006-12 |
|
| Fungal bioconversion of toxic polychlorinated biphenyls by white-rot fungus, Phlebia brevispora. | 2006-12 |
|
| Toxicology and carcinogenesis studies of a binary mixture of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (Cas No. 57465-28-8) and 2,3',4,4',5-pentachlorobiphenyl (PCB 118) (Cas No. 31508-00-6) in female Harlan Sprague-Dawley rats (gavage studies). | 2006-11 |
|
| Application of an ELISA for PCB 118 to the screening of dioxin-like PCBs in retail fish. | 2006-10 |
|
| Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls after purification with active charcoal. | 2006-09-10 |
|
| Cytochrome P450 1A4 and 1A5 in common cormorant (Phalacrocorax carbo): evolutionary relationships and functional implications associated with dioxin and related compounds. | 2006-08 |
|
| Effects of single non-ortho, mono-ortho, and di-ortho chlorinated biphenyls on human sperm functions in vitro. | 2006-04 |
|
| Relative potencies of PAHs and PCBs based on the response of human cells. | 1999-03 |
|
| Response of xenobiotic metabolizing enzymes of rainbow trout (Oncorhynchus mykiss) to the mono-ortho substituted polychlorinated PCB congener 2,3',4,4',5-pentachlorobiphenyl, PCB-118, detected by enzyme activities and immunochemical methods. | 1991-04 |
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31508-00-6
Created by
admin on Mon Mar 31 19:32:08 GMT 2025 , Edited by admin on Mon Mar 31 19:32:08 GMT 2025
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35823
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DTXSID4032116
Created by
admin on Mon Mar 31 19:32:08 GMT 2025 , Edited by admin on Mon Mar 31 19:32:08 GMT 2025
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2B2AQE8U50
Created by
admin on Mon Mar 31 19:32:08 GMT 2025 , Edited by admin on Mon Mar 31 19:32:08 GMT 2025
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PRIMARY |
SUBSTANCE RECORD
