DENAVERINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H33NO3.ClH
Molecular Weight	419.985
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCC(CC)COC(C(=O)OCCN(C)C)(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=RSDBEODKTNUEMS-UHFFFAOYSA-N

InChI=1S/C24H33NO3.ClH/c1-5-20(6-2)19-28-24(21-13-9-7-10-14-21,22-15-11-8-12-16-22)23(26)27-18-17-25(3)4;/h7-16,20H,5-6,17-19H2,1-4H3;1H

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Description
Sources: https://www.ema.europa.eu/en/documents/mrl-report/denaverine-hydrochloride-summary-report-committee-veterinary-medicinal-products_en.pdf | https://www.ncbi.nlm.nih.gov/pubmed/29902814 | https://www.ncbi.nlm.nih.gov/pubmed/3936060

Denaverine is a benzilacid derivative. It is a phenobarbital-type microsomal enzyme inducer. Denaverine has a relaxing effect on the prepartum uterus and provides an increased flexibility of the soft birth canal. In addition, it has a surface anaestetic effect and an anticonvulsive effect as well as a slightly tranquilizing and antipyretic effect. In veterinary medicine denaverine hydrochloride is used to regulate myometrial contractions during parturition. It is a regularly used substance in obstetrics in veterinary medicine in many European countries.

Approval Year

Patents

Sample Use Guides

In Vivo Use Guide

Oral: 60 to 270 mg per person Par rectum: 100 to 400 mg per person Parenterally: 40 to 160 mg per person

Route of Administration: Other

Name

Type

Language

DENAVERINE HYDROCHLORIDE

Common Name

English

DENAVERINE HCL

Common Name

English

Denaverine hydrochloride [WHO-DD]

Common Name

English

2-(DIMETHYLAMINO)ETHYL (2-ETHYLBUTOXY)DIPHENYLACETATE HYDROCHLORIDE

Systematic Name

English

ACETIC ACID, (2-ETHYLBUTOXY)DIPHENYL-, 2-(DIMETHYLAMINO)ETHYL ESTER HYDROCHLORIDE

Common Name

English

BENZENEACETIC ACID, .ALPHA.-(2-ETHYLBUTOXY)-.ALPHA.-PHENYL-, 2-(DIMETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE

Common Name

English

SPASMALGAN

Brand Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66880