XANTHATIN

[H][C@]12C[C@H](C)C(\C=C\C(C)=O)=CC[C@]1([H])C(=C)C(=O)O2

InChIKey=RBRPTFMVULVGIC-ZTIIIDENSA-N

InChI=1S/C15H18O3/c1-9-8-14-13(11(3)15(17)18-14)7-6-12(9)5-4-10(2)16/h4-6,9,13-14H,3,7-8H2,1-2H3/b5-4+/t9-,13+,14-/m0/s1

Targets

Primary Target	Pharmacology	Potency
Tyrosine-protein kinase JAK2 55 Target ID: CHEMBL2971 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30993883	Inhibitor 8297	4.1 µM [IC50]
Inhibitor of nuclear factor kappa B kinase beta subunit 16 Target ID: CHEMBL1991 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30993883	Inhibitor 8297	11.3 µM [IC50]
Vascular endothelial growth factor receptor 2 104 Target ID: CHEMBL279 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26617743	Inhibitor 8297	3.8 µM [IC50]

PubMed

Title	Date	PubMed

Name

Type

Language

XANTHATIN

Common Name

English

XANTHATIN, (-)-

Common Name

English

(-)-XANTHATIN

Common Name

English

XANTHATIN [MI]

Common Name

English

2H-CYCLOHEPTA(B)FURAN-2-ONE, 3,3A,4,7,8,8A-HEXAHYDRO-7-METHYL-3-METHYLENE-6-((1E)-3-OXO-1-BUTEN-1-YL)-, (3AR,7S,8AS)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

5281511