Stereochemistry | ACHIRAL |
Molecular Formula | C12H13N4O2S.Na |
Molecular Weight | 300.312 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].CC1=CC([N-]S(=O)(=O)C2=CC=C(N)C=C2)=NC(C)=N1
InChI
InChIKey=XTXYCJOBMKKQOW-UHFFFAOYSA-N
InChI=1S/C12H13N4O2S.Na/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11;/h3-7H,13H2,1-2H3;/q-1;+1
Sulfisomidine (INN), also known as sulphasomidine (BAN until 2003), is a sulfonamide antibacterial. It’s used in the treatment, control, prevention, and improvement of the following conditions and symptoms: Lower urinary tract infections; Meningococcal meningitis; Streptococcal pharyngitis; Gum infection; Bacillary dysentery.
Approval Year
Sourcing
PubMed
Patents
Sample Use Guides
The monotherapy of S suis infections with sulfonamides (SULFISOMIDINE was one of them) should not be encouraged because the MIC50 of all sulfonamides investigated was greater than 32 micrograms/ml. The MIC50 of the sulfonamides against B bronchiseptica ranged from 0.5 to 8 micrograms/ml, against P multocida from 2 to 32 micrograms/ml, and against H pleuropneumoniae from 8 to 64 micrograms/ml.