Elfucose

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C6H12O5
Molecular Weight	164.1565
Optical Activity	( - )
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O

InChI

InChIKey=PNNNRSAQSRJVSB-KCDKBNATSA-N

InChI=1S/C6H12O5/c1-3(8)5(10)6(11)4(9)2-7/h2-6,8-11H,1H3/t3-,4+,5+,6-/m0/s1

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Studies on the plasma membrane of normal and psoriatic keratinocytes. 6. Cell surface and shed glycoproteins.	1983 Jan	6184420
Lectin cytochemical evaluation of somatosensory neurons and their peripheral and central processes in rat and man.	1986	3757018
Fucosyltransferases: differential plasma and tissue alterations in hepatocellular carcinoma and cirrhosis.	1991 Apr	1849114
A monoclonal IgM kappa from a blood group B individual with specificity for alpha-galactosyl epitopes on partially hydrolyzed blood group B substance.	1993 May 7	7688662
Monoclonal antibody FW6 defines an epitope on alpha 3/4-monofucosylated polylactosaminoglycans expressed by fetal and colon carcinoma-associated mucins.	1993 Sep 15	8364932
750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma.	1995 Mar 1	7762816
O-linked L-fucose is present in Desmodus rotundus salivary plasminogen activator.	1996 Mar 29	8631761
Effect of L-fucose and D-glucose concentration on L-fucoprotein metabolism in human Hep G2 cells and changes in fucosyltransferase and alpha-L-fucosidase activity in liver of diabetic rats.	1997 Apr 17	9133643
Sialyl Lewis(x) epitopes do not occur on acute phase proteins in mice: relationship to the absence of alpha3-fucosyltransferase in the liver.	1998 Apr	9613826
The metabolism of 6-deoxyhexoses in bacterial and animal cells.	1998 Nov	9893952
Human epidermal Langerhans cells express the mannose-fucose binding receptor.	1998 Nov	9842897
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily.	1998 Nov 15	9817848
Substrate discrimination by the human GTP fucose pyrophosphorylase.	2005 Aug 16	16086588
Human symbionts use a host-like pathway for surface fucosylation.	2005 Mar 18	15774760
Molecular cloning and characterization of a novel human beta1,3-glucosyltransferase, which is localized at the endoplasmic reticulum and glucosylates O-linked fucosylglycan on thrombospondin type 1 repeat domain.	2006 Dec	16899492

Patents

Name

Type

Language

Elfucose

Official Name

English

FUCOSE

Preferred Name

English

L-FUCOSE

Common Name

English

6-deoxy-L-galactose

Systematic Name

English

elfucose [INN]

Common Name

English

ELFUCOSE [USAN]

Common Name

English

(-)-FUCOSE

Common Name

English

DEOXYGALACTOSE-CERECOR

Common Name

English

FUCOSE, L-

Common Name

English

6-deoxy-L-galactopyranose

Common Name

English

L-FUCOSE [MI]

Common Name

English

FUCOSE-CERECOR

Common Name

English

FUCOSE [INCI]

Common Name

English

L-(-)-FUCOSE

Common Name

English

L-FUCOSE [USP-RS]

Common Name

English

NSC-1219

Code

English

L-GALACTOMETHYLOSE

Common Name

English

L-fucopyranose

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

667018