U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Name Type Language
VUTRISIRAN SODIUM
Official Name English
ALN-TTRSC02
Code English
ALN-65492 SODIUM
Code English
Vutrisiran sodium [WHO-DD]
Common Name English
VUTRISIRAN SODIUM [JAN]
Common Name English
AMVUTTRA
Brand Name English
RNA, (Um-sp-(2'-deoxy-2'-fluoro)C-sp-Um-Um-Gm-(2'-deoxy-2'-fluoro)G-UmUm-(2'-deoxy-2'-fluoro)A-Cm-Am-Um-Gm-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy2'-fluoro)A-Um-Cm-Cm-Cm-Am-sp-Um-sp-Cm), complex with RNA (Um-spGm-sp-Gm-Gm-Am-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-de
Systematic Name English
VOTRISIRAN SODIUM
Official Name English
Code System Code Type Description
RXCUI
2605574
Created by admin on Sat Dec 16 14:56:44 GMT 2023 , Edited by admin on Sat Dec 16 14:56:44 GMT 2023
PRIMARY
FDA UNII
28O0WP6Z1P
Created by admin on Sat Dec 16 14:56:44 GMT 2023 , Edited by admin on Sat Dec 16 14:56:44 GMT 2023
PRIMARY
Sugar Site Range Site Count
2'-O-Methyl-Ribose 1_1-1_6;1_8;1_12-1_22;2_1;2_3-2_5;2_7-2_8;2_10-2_13;2_15;2_17-2_23 36 / 45
2'-Fluoro-Ribose 1_7;1_9-1_11;2_2;2_6;2_9;2_14;2_16 9 / 45
Linkage Site Range Site Count
Sodium Phosporothioate 1_2-1_3;2_2-2_3;2_22-2_23 6 / 43
1_4-1_22;2_4-2_21 37 / 43