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Details

Stereochemistry ACHIRAL
Molecular Formula C4H9NO.ClH
Molecular Weight 123.581
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Morpholine hydrochloride

SMILES

Cl.C1COCCN1

InChI

InChIKey=JXYZHMPRERWTPM-UHFFFAOYSA-N
InChI=1S/C4H9NO.ClH/c1-3-6-4-2-5-1;/h5H,1-4H2;1H

HIDE SMILES / InChI
Morpholine salicylate is a derivative of salicylic acid. It is a non-steroidal anti-inflammatory drug and was marketed under a tradename Retarcyl, Dolical and Deposal.

Approval Year

PubMed

PubMed

TitleDatePubMed
Novel piperidinyloxy oxazolidinone antibacterial agents. Diversification of the N-Substituent.
2002-07
The zebrafish as a model for human disease.
2002-06-01
A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo.
2002-06-01
Multiple functions of a Zic-like gene in the differentiation of notochord, central nervous system and muscle in Ciona savignyi embryos.
2002-06
Metabolites of orally active NO-independent pyrazolopyridine stimulators of soluble guanylate cyclase.
2002-06
Intramural coronary delivery of advanced antisense oligonucleotides reduces neointimal formation in the porcine stent restenosis model.
2002-05-15
A dominant-negative form of p63 is required for epidermal proliferation in zebrafish.
2002-05
Fgf3 and Fgf8 are required together for formation of the otic placode and vesicle.
2002-05
The IGF pathway regulates head formation by inhibiting Wnt signaling in Xenopus.
2002-04-15
Axial protocadherin is a mediator of prenotochord cell sorting in Xenopus.
2002-04-15
Thiourea derivatives and their nickel(II) and platinum(II) complexes: antifungal activity.
2002-04-10
Adamantyl tenocyclidines--adjuvant therapy in poisoning with organophosphorus compounds and carbamates.
2002-04
Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats.
2002-04
Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.
2002-04
LvDelta is a mesoderm-inducing signal in the sea urchin embryo and can endow blastomeres with organizer-like properties.
2002-04
Expression of ROCK-1 in human pancreatic cancer: its down-regulation by morpholino oligo antisense can reduce the migration of pancreatic cancer cells in vitro.
2002-04
Relationship between lipophilicity and antitumor activity of molecule library of Mannich ketones determined by high-performance liquid chromatography, clogP calculation and cytotoxicity test.
2002-03-05
The planar polarity gene strabismus regulates convergent extension movements in Xenopus.
2002-03-01
Multiple interactions between maternally-activated signalling pathways control Xenopus nodal-related genes.
2002-03
In vitro studies indicate that acid catalysed generation of N-nitrosocompounds from dietary nitrate will be maximal at the gastro-oesophageal junction and cardia.
2002-03
macho-1-Related genes in Ciona embryos.
2002-03
Tumor pretargeting in mice using (99m)Tc-labeled morpholino, a DNA analog.
2002-03
her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis.
2002-03
Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration.
2002-02-08
Anchor-based design of improved cholera toxin and E. coli heat-labile enterotoxin receptor binding antagonists that display multiple binding modes.
2002-02
Conformationally restrained analogues of sympathomimetic catecholamines. Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2',5'-morpholines].
2002-01
The transcription factor Sox9 is required for cranial neural crest development in Xenopus.
2002-01
2001: a mouse genome odyssey.
2002
O-Phosphonatomethylcholine, its analogues, alkyl esters, and their biological activity.
2001-12-06
Reactions with pyrrolidine-2,4-diones, Part 4: Synthesis of some 3-substituted 1,5-diphenylpyrrolidine-2,4-diones as potential antimicrobial, anti-HIV-1 and antineoplastic agents.
2001-12
Morpholinium 2-chloro-4-nitrobenzoate, 2-chloro-5-nitrobenzoate and 4-chloro-3-nitrobenzoate.
2001-12
Expression of c-myc is not critical for cell proliferation in established human leukemia lines.
2001-11-16
Gridlock signalling pathway fashions the first embryonic artery.
2001-11-08
Optimization of 4-phenylamino-3-quinolinecarbonitriles as potent inhibitors of Src kinase activity.
2001-11-08
Shellac formulations to reduce epiphytic survival of coliform bacteria on citrus fruit postharvest.
2001-11
Effect of new synthetic growth regulators, isomeric 1-(dimethyloctyl), 1-alkylpiperidinium and morpholinium halides on morphogenesis of Aster chinensis L. as a function of their molecular structure.
2001-10-19
In vitro selection of allosteric ribozymes: theory and experimental validation.
2001-10-05
Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers.
2001-10
trans-2,4,4,6,8,8-Hexamorpholino-2,6-bis(n-propylamino)cyclo-2lambda5,4lambda5,6lambda5,8lambda5-tetraphosphazatetraene.
2001-10
Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development.
2001-10
Polar nitrogen compounds and their behaviour in the drinking water treatment process.
2001-10
The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish.
2001-09-15
Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo.
2001-09
Early embryonic expression of a LIM-homeobox gene Cs-lhx3 is downstream of beta-catenin and responsible for the endoderm differentiation in Ciona savignyi embryos.
2001-09
XMeis3 protein activity is required for proper hindbrain patterning in Xenopus laevis embryos.
2001-09
Zebrafish wnt8 encodes two wnt8 proteins on a bicistronic transcript and is required for mesoderm and neurectoderm patterning.
2001-07
Inhibition of RNA synthesis in vitro and cell growth by anthracycline antibiotics.
2001
Final report on the safety assessment of Cetethyl Morpholinium Ethosulfate.
2001
Learning the language of cell-cell communication through connexin channels.
2001
An amphibian with ambition: a new role for Xenopus in the 21st century.
2001
Patents
Name Type Language
MORPHOLINE HCL
Preferred Name English
Morpholine hydrochloride
MI  
Systematic Name English
MORPHOLINIUM CHLORIDE
Systematic Name English
MORPHOLINE, HYDROCHLORIDE
Systematic Name English
MORPHOLINE HYDROCHLORIDE [MI]
Common Name English
MORPHOLINE, HYDROCHLORIDE (1:1)
Systematic Name English
Code System Code Type Description
FDA UNII
28G373717I
Created by admin on Mon Mar 31 19:34:24 GMT 2025 , Edited by admin on Mon Mar 31 19:34:24 GMT 2025
PRIMARY
MESH
C037574
Created by admin on Mon Mar 31 19:34:24 GMT 2025 , Edited by admin on Mon Mar 31 19:34:24 GMT 2025
PRIMARY
MERCK INDEX
m7632
Created by admin on Mon Mar 31 19:34:24 GMT 2025 , Edited by admin on Mon Mar 31 19:34:24 GMT 2025
PRIMARY Merck Index
CAS
10024-89-2
Created by admin on Mon Mar 31 19:34:24 GMT 2025 , Edited by admin on Mon Mar 31 19:34:24 GMT 2025
PRIMARY
PUBCHEM
197884
Created by admin on Mon Mar 31 19:34:24 GMT 2025 , Edited by admin on Mon Mar 31 19:34:24 GMT 2025
PRIMARY
EPA CompTox
DTXSID40905287
Created by admin on Mon Mar 31 19:34:24 GMT 2025 , Edited by admin on Mon Mar 31 19:34:24 GMT 2025
PRIMARY
ECHA (EC/EINECS)
233-029-4
Created by admin on Mon Mar 31 19:34:24 GMT 2025 , Edited by admin on Mon Mar 31 19:34:24 GMT 2025
PRIMARY