METOFENAZATE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C31H36ClN3O5S
Molecular Weight	598.153
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of METOFENAZATE

Structure Search

SMILES

COC1=CC(=CC(OC)=C1OC)C(=O)OCCN2CCN(CCCN3C4=CC=CC=C4SC5=CC=C(Cl)C=C35)CC2

InChI

InChIKey=BAQLUVXNKOTTHU-UHFFFAOYSA-N

InChI=1S/C31H36ClN3O5S/c1-37-26-19-22(20-27(38-2)30(26)39-3)31(36)40-18-17-34-15-13-33(14-16-34)11-6-12-35-24-7-4-5-8-28(24)41-29-10-9-23(32)21-25(29)35/h4-5,7-10,19-21H,6,11-18H2,1-3H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2449225

Metofenazate is a calmodulin inhibitor and was studied as an antipsychotic drug.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Metofenazate as a more selective calmodulin inhibitor than trifluoperazine.	1987-09	2449225

Name

Type

Language

METOFENAZATE

Official Name

English

METOFENAZATE [MI]

Preferred Name

English

Metofenazate [WHO-DD]

Common Name

English

2-(4-(3-(2-CHLOROPHENOTHIAZIN-10-YL)PROPYL)-1-PIPERAZINYL)ETHYL 3,4,5-TRIMETHOXYBENZOATE

Systematic Name

English

metofenazate [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C740

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

Code System Code Type Description

EVMPD

SUB08903MIG

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

ChEMBL

CHEMBL2105229

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

NCI_THESAURUS

C66132

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

CAS

388-51-2

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

PUBCHEM

9800

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

MERCK INDEX

m7491

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

Merck Index

FDA UNII

27J5OW8OGT

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

SMS_ID

100000080938

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

EPA CompTox

DTXSID50192065

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

MESH

C008520

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

CHEBI

59116

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

INN

2110

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

DRUG CENTRAL

3357

Created by admin on Mon Mar 31 18:06:58 GMT 2025 , Edited by admin on Mon Mar 31 18:06:58 GMT 2025

PRIMARY

ACTIVE MOIETY


					27J5OW8OGT