Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C6H12N2O3.ClH |
Molecular Weight | 196.632 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.NCCO\C=C\[C@H](N)C(O)=O
InChI
InChIKey=ZDCPLYVEFATMJF-BTIOQYSDSA-N
InChI=1S/C6H12N2O3.ClH/c7-2-4-11-3-1-5(8)6(9)10;/h1,3,5H,2,4,7-8H2,(H,9,10);1H/b3-1+;/t5-;/m0./s1
Aminoethoxyvinylglycine (Aviglycine, AVG) is a plant regulator used on
apples, pears, and ornamentals. In apples, it may delay fruit maturity, leading to
benefits such as a reduction in pre-harvest fruit drop and improved fruit quality. In
pears, AVG may help maintain fruit firmness. For specific ornamentals (miniature
carnations, hibiscus, and rooted geranium cuttings and seedlings), AVG may
reduce problems, such as flower senescence and flower bud abscission, that occur
during shipping. AVG to be used as a spray solution, applied to apples or pears as a
single application 28 days prior to the anticipated beginning of the normal harvest
period, and to specified ornamentals 24-to -48 hours prior to boxing/shipping.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: GO:0009693 |
|||
Target ID: P32929 Gene ID: 1491.0 Gene Symbol: CTH Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/10212249 |
10.5 µM [Ki] | ||
Target ID: GO:0009693 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Sample Use Guides
In Vivo Use Guide
Sources: https://apvma.gov.au/sites/default/files/publication/13586-prs-aminoethoxyvinylglycine.pdf
Curator's Comment: Aminoethoxyvinylglycine (Aviglycine, AVG) was of low oral toxicity in rats (LD50 = 6480 mg/kg bw), low dermal toxicity in rabbits
(LD50 >2000 mg/kg bw, no deaths) and moderate inhalation toxicity in rats (LC50 = 1130
mg/m3). It was a slight skin irritant and a moderate eye irritant in rabbits, but was not a skin
sensitiser in guinea pigs.
Following a single oral dose of 2.25 or 50 mg/kg bw of 14C-AVG to rats, absorption was
rapid and extensive, although not complete (over 80% of the administered dose), and
excretion was prolonged over many days. The primary route of excretion was via the urine
(approximately 57 to 74%) with faecal excretion a minor route (11.4 to 13.6%). Elimination
in expired air was substantial at a dose of 2.25 mg/kg bw (18 to 22%) but much less
significant at 50 mg/kg bw (4.8%). AVG was not a teratogen when administered to pregnant rats during the period of foetal
organ formation at oral doses of 0, 0.5, 2.2 or 10 mg/kg bw/day.
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/24226701
The presence of 1-10 uM Aminoethoxyvinylglycine (Aviglycine, AVG) or 5-30 uM AgNO3 markedly enhanced shoot regeneration from cotyledon and hypocotyl cultures of eight recalcitrant Brassica campestris and B. juncea genotypes tested.
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EPA PESTICIDE CODE |
129104
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admin on Sat Dec 16 03:00:38 GMT 2023 , Edited by admin on Sat Dec 16 03:00:38 GMT 2023
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266URI8C56
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DTXSID1034266
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55720-26-8
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m1704
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16211101
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aviglycine hydrochloride
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admin on Sat Dec 16 03:00:38 GMT 2023 , Edited by admin on Sat Dec 16 03:00:38 GMT 2023
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SUBSTANCE RECORD