IMPACARZINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

First approved in 2020

Possibly Marketed Outside US

First approved in 2020

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H55N5O2
Molecular Weight	493.7686
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of IMPACARZINE

Structure Search

SMILES

CCCCCCCCCCCCCCN1CCN(CCN2CCN(CC2)C(=O)N(CC)CC)C1=O

InChI

InChIKey=OQXWEZVLEIJVSI-UHFFFAOYSA-N

InChI=1S/C28H55N5O2/c1-4-7-8-9-10-11-12-13-14-15-16-17-18-31-25-26-33(28(31)35)24-21-29-19-22-32(23-20-29)27(34)30(5-2)6-3/h4-26H2,1-3H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/525526 | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19730412&CC=DE&NR=2150438A1&KC=A1

Impacarzine is cyclic urea derivative patented by pharmaceutical company Asta-Werke A.-G. as antiviral agent. In preclinical models Impacarzine gave 25% protection to mice infected with Influenza A2/Hongkong virus.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Influence of a new virostatic compound on the induction of enzymes in rat liver.	1975 Sep	24

Patents

Patents

Sample Use Guides

In Vivo Use Guide

mice: 10 mg/kg

Route of Administration: Oral

Name

Type

Language

IMPACARZINE

Official Name

English

N,N-DIETHYL-4-(2-(2-OXO-3-TETRADECYL-1-IMIDAZOLIDINYL)ETHYL)-1-PIPERAZINECARBOXAMIDE

Systematic Name

English

impacarzine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C281

Created by admin on Fri Dec 15 16:01:09 GMT 2023 , Edited by admin on Fri Dec 15 16:01:09 GMT 2023

Code System Code Type Description

EPA CompTox

DTXSID90194301

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ChEMBL

CHEMBL2104823

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SMS_ID

100000083364

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NCI_THESAURUS

C65900

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DAILYMED

25G65PH99M

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ECHA (EC/EINECS)

255-324-7

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EVMPD

SUB08158MIG

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RXCUI

2367441

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CAS

41340-39-0

Created by admin on Fri Dec 15 16:01:09 GMT 2023 , Edited by admin on Fri Dec 15 16:01:09 GMT 2023

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PUBCHEM

3033979

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FDA UNII

25G65PH99M

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INN

4072

Created by admin on Fri Dec 15 16:01:09 GMT 2023 , Edited by admin on Fri Dec 15 16:01:09 GMT 2023

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ACTIVE MOIETY


					25G65PH99M