Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H5N3O2 |
| Molecular Weight | 163.1335 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[O-][N+](=O)C1=CC=C2NN=CC2=C1
InChI
InChIKey=WSGURAYTCUVDQL-UHFFFAOYSA-N
InChI=1S/C7H5N3O2/c11-10(12)6-1-2-7-5(3-6)4-8-9-7/h1-4H,(H,8,9)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors. | 2011-08 |
|
| Selective electrochemical discrimination between dopamine and phenethylamine-derived psychotropic drugs using electrodes modified with an acyclic receptor containing two terminal 3-alkoxy-5-nitroindazole rings. | 2010-06 |
|
| ESR and electrochemical study of 1,2-disubstituted 5-nitroindazolin-3-ones and 2-substituted 3-alkoxy-5-nitro-2H-indazoles: reactivity and free radical production capacity in the presence of biological systems. | 2010-01 |
|
| New potent 5-nitroindazole derivatives as inhibitors of Trypanosoma cruzi growth: synthesis, biological evaluation, and mechanism of action studies. | 2009-12-15 |
|
| Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO). | 2009-10 |
|
| Molecular encapsulation of 5-nitroindazole derivatives in 2,6-dimethyl-beta-cyclodextrin: electrochemical and spectroscopic studies. | 2009-07-01 |
|
| Study of 5-nitroindazoles' anti-Trypanosoma cruzi mode of action: electrochemical behaviour and ESR spectroscopic studies. | 2009-04 |
|
| In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles. | 2009-03 |
|
| Comparative spectroscopic and electrochemical study of nitroindazoles: 3-alcoxy, 3-hydroxy and 3-oxo derivatives. | 2008-08 |
|
| Characterization, phase-solubility, and molecular modeling of inclusion complex of 5-nitroindazole derivative with cyclodextrins. | 2008-05-01 |
|
| ESR and electrochemical study of 5-nitroindazole derivatives with antiprotozoal activity. | 2006-01 |
|
| Synthesis and biological properties of new 5-nitroindazole derivatives. | 2005-05-02 |
|
| Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency. | 2002-11-26 |
Patents
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226-451-5
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5032
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21501
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DB04534
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DTXSID5049316
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235Y7P37ZD
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5401-94-5
Created by
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SUBSTANCE RECORD
