ZENAZOCINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C23H35NO2
Molecular Weight	357.5295
Optical Activity	( + / - )
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)CCC(=O)CC[C@]1(C)[C@H]2CC3=C(C=C(O)C=C3)[C@]1(C)CCN2C

InChI

InChIKey=JZFZEWWOIOYBTQ-XPWALMASSA-N

InChI=1S/C23H35NO2/c1-16(2)6-8-18(25)10-11-23(4)21-14-17-7-9-19(26)15-20(17)22(23,3)12-13-24(21)5/h7,9,15-16,21,26H,6,8,10-14H2,1-5H3/t21-,22+,23-/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2860595 | https://doi.org/10.1016/S0065-7743(08)61029-5

Zenazocine is an opioid analgesic that mixes both agonist/antagonist activities. This compound participated in phase II clinical trial, however, the further development was ultimately halted and it has never been marketed.

Approval Year

PubMed

Title	Date	PubMed
Pharmacological profiles of tonazocine (Win 42156) and zenazocine (Win 42964).	1985-02	2860595

Patents

Name

Type

Language

WIN-42964

Preferred Name

English

ZENAZOCINE

Common Name

English

3-HEPTANONE, 1-((2R,6S,11S)-1,2,3,4,5,6-HEXAHYDRO-8-HYDROXY-3,6,11-TRIMETHYL-2,6-METHANO-3-BENZAZOCIN-11-YL)-6-METHYL-, REL-

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID20998516