U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2Na.HO4P
Molecular Weight 141.9588
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM PHOSPHATE, DIBASIC, ANHYDROUS

SMILES

[Na+].[Na+].OP([O-])([O-])=O

InChI

InChIKey=BNIILDVGGAEEIG-UHFFFAOYSA-L
InChI=1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2

HIDE SMILES / InChI

Description

Phosphoric acid, also known as orthophosphoric acid, is used in dentistry and orthodontics to clean and roughen the surfaces of teeth where dental appliances or fillings will be placed. In addition, this acid is a part of product ProcalAmine, which is indicated for peripheral administration in adults to preserve body protein and improve nitrogen balance in well-nourished, mildly catabolic patients who require short-term parenteral nutrition. In combination with dextrose (glucose) and levulose (fructose), phosphoric acid relieves nausea due to upset stomach from intestinal flu, stomach flu, and food or drink indiscretions. In addition, homeopathic product, Brain power contains also phosphoric acid and this product is used to temporarily relieve symptoms of general physical weakness and listlessness, including: fatigue; sore muscles & joints; dry skin; absence of sexual desire; occasional sleeplessness.

Approval Year

1921
1467
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Approved
8429
PROCALAMINE

Approved Use

ProcalAmine is indicated for peripheral administration in adults to preserve body protein and improve nitrogen balance in well-nourished, mildly catabolic patients who require short-term parenteral nutrition.

Launch Date

1982
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Diagnostic
Natural Metabolite
Unknown

Approved Use

Unknown
Diagnostic
Natural Metabolite
Unknown

Approved Use

Unknown
Primary
Approved
8429
SODIUM PHOSPHATES INJECTION

Approved Use

Sodium Phosphates Injection, USP, 3mM P/mL, is indicated as a source of phosphorus, for addition to large volume intravenous fluids, to prevent or correct hypophosphatemia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions. The concomitant amount of sodium (4 mEq/mL) must be calculated into total electrolyte content of such prepared solutions.
PubMed

PubMed

TitleDatePubMed
Diurnal variation in the levels of glucose and related substances in healthy and diabetic subjects during starvation.
1967 Feb
Determination of inorganic phosphate in serum and saliva using a synthetic receptor.
2003 Jun 12
Amperometric biosensor for determining human salivary phosphate.
2005 Aug 15
Phosphorus amendment reduces hepatic and renal oxidative stress in mallards ingesting lead-contaminated sediments.
2006 Jun
Patents

Patents

04224407
30
04355158
29
04487752
28
04533660
37
04537718
27
04565680
30
04613463
35
04744965
27
04780452
28
04812462
29
04886910
30
05374392
27
05387697
27
05415807
29
05444050
28
05496930
27
05525524
27
05635391
27
05698229
27
05910504
29
05916781
27
05917041
35
05928933
27
05962694
28
05994368
29
06017919
28
06028035
27
06096689
27
06165944
27
06197973
27
06258829
27
06399627
28
06528514
27
06576596
27
06657060
27
06737417
27
06821980
27
06864367
28
06867198
27
06903217
29
06916837
27
06924310
28
06933365
27
06958347
27
06974639
27
06989391
31
06992087
30
07005440
29
07045551
27
07074801
32
07087609
27
07094801
30
07115611
29
07169944
27
07176216
27
07179912
27
07196081
32
07223762
27
07230023
29
07247731
40
07273882
27
07314888
29
07317012
27
07323569
29
07332511
32
07338963
30
07345068
28
07354662
27
07432287
27
07432375
27
07439237
27
07446216
27
07449477
27
07456196
28
07456218
27
07507739
36
07517894
27
07524951
27
07531535
29
07544690
30
07560582
40
07563901
27
07582754
31
07582803
35
07589199
30
07592358
29
07595178
27
07595314
29
07632850
27
07655664
28
07700589
28
07737166
33
07749992
30
07772285
30
07829563
28
07834030
30
07906517
31
07947711
27
07951797
27
07968720
27
07994336
29
07998995
28
08008321
27
08017610
30
08039479
29
08063099
31
08067583
27
08080541
30
08143446
28
08153653
27
08173812
27
08173824
27
08211927
27
08221905
27
08273767
28
08304411
28
08313671
27
08324216
27
08324219
28
08372858
30
08377921
29
08394830
28
08394842
27
08399450
29
08404673
29
08415349
29
08415359
29
08436024
27
08481579
27
08492582
27
08497397
28
08501732
37
08524751
27
08524909
29
08536197
29
08546588
29
08569341
29
08586204
27
08591943
28
08609675
28
08618094
28
08629144
28
08633216
27
08658117
27
08674111
28
08674141
28
08680120
29
08703784
27
08709615
27
08791139
28
08841467
27
08846746
27
20020025910
30
20030003160
27
20120070359
27
20140171390
27
2600813
27
US3382035
27

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
SODIUM PHOSPHATE, DIBASIC, ANHYDROUS
II   ORANGE BOOK  
Common Name English
DIBASIC SODIUM PHOSPHATE, ANHYDROUS
Common Name English
DISODIUM HYDROGEN PHOSPHATE, ANHYDROUS
Common Name English
DISODIUM HYDROGEN PHOSPHATE ANHYDROUS
Common Name English
VISICOL COMPONENT SODIUM PHOSPHATE, DIBASIC ANHYDROUS
Common Name English
OSMOPREP COMPONENT SODIUM PHOSPHATE, DIBASIC ANHYDROUS
Common Name English
SODIUM PHOSPHATE, DIBASIC [MI]
Common Name English
SODIUM PHOSPHATE, DIBASIC, ANHYDROUS [ORANGE BOOK]
Common Name English
INS NO.339(II)
Code English
SODIUM MONOHYDROGEN PHOSPHATE
Common Name English
PHOSPHORIC ACID, SODIUM SALT (1:2)
Common Name English
DISODIUM HYDROGEN PHOSPHATE
Systematic Name English
SODIUM PHOSPHATE DIBASIC ANHYDROUS
Common Name English
SODIUM PHOSPHATE DIBASIC
WHO-DD  
Common Name English
SODIUM PHOSPHATE, DIBASIC ANHYDROUS [ORANGE BOOK]
Common Name English
SODIUM PHOSPHATE,DIBASIC,ANHYDROUS [VANDF]
Common Name English
Sodium phosphate dibasic [WHO-DD]
Common Name English
DISODIUM HYDROGEN MONOPHOSPHATE
Systematic Name English
SODIUM PHOSPHATE, DIBASIC, ANHYDROUS [II]
Common Name English
SODIUM PHOSPHATE, DIBASIC ANHYDROUS
ORANGE BOOK  
Common Name English
DISODIUM PHOSPHATE [INCI]
Common Name English
SECONDARY SODIUM PHOSPHATE
Common Name English
INS-339(II)
Code English
FEMA NO. 2398
Code English
SODIUM PHOSPHATE, DIBASIC ANHYDROUS COMPONENT OF OSMOPREP
Common Name English
E-339(II)
Code English
DISODIUM PHOSPHATE [EP MONOGRAPH]
Common Name English
EXSICCATED SODIUM PHOSPHATE
Common Name English
PHOSPHORIC ACID, DISODIUM SALT, ANHYDROUS
Common Name English
DISODIUM PHOSPHATE, ANHYDROUS
Common Name English
SODIUM PHOSPHATE, DIBASIC ANHYDROUS COMPONENT OF VISICOL
Common Name English
DISODIUM ACID PHOSPHATE
Common Name English
SODIUM PHOSPHATE [FHFI]
Common Name English
DISODIUM PHOSPHATE [HSDB]
Common Name English
DIBASIC SODIUM PHOSPHATE ANHYDROUS
Common Name English
ACETEST
Common Name English
DISODIUM PHOSPHATE
HSDB   INCI  
INCI  
Official Name English
Classification Tree Code System Code
CODEX ALIMENTARIUS (GSFA) INS-339(II)
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
CFR 21 CFR 175.210
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
EPA PESTICIDE CODE 76403
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
CFR 21 CFR 522.161
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
NCI_THESAURUS C29730
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
Code System Code Type Description
FDA UNII
22ADO53M6F
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
NCI_THESAURUS
C66546
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
SMS_ID
100000076102
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
EVMPD
SUB12491MIG
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
CHEBI
34683
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
PUBCHEM
24203
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
ChEMBL
CHEMBL1060
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
DAILYMED
22ADO53M6F
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
JECFA EVALUATION
INS-339(II)
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
HSDB
376
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
EPA CompTox
DTXSID1026039
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
DRUG BANK
DB09127
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
EVMPD
SUB11915MIG
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
MESH
C018279
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
WIKIPEDIA
DISODIUM PHOSPHATE
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
ECHA (EC/EINECS)
231-448-7
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
RXCUI
314838
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY RxNorm
CAS
7558-79-4
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY
MERCK INDEX
m10059
Created by admin on Fri Dec 15 15:42:28 GMT 2023 , Edited by admin on Fri Dec 15 15:42:28 GMT 2023
PRIMARY Merck Index
ACTIVE MOIETY
Structure of PHOSPHATE ION
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966