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Details

Stereochemistry RACEMIC
Molecular Formula C4H9NO3
Molecular Weight 119.1192
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of .GAMMA.-AMINO-.BETA.-HYDROXYBUTYRIC ACID

SMILES

NCC(O)CC(O)=O

InChI

InChIKey=YQGDEPYYFWUPGO-UHFFFAOYSA-N
InChI=1S/C4H9NO3/c5-2-3(6)1-4(7)8/h3,6H,1-2,5H2,(H,7,8)

HIDE SMILES / InChI

Description

4-Amino-3-hydroxybutanoic acid (GABOB) is an endogenous ligand found in the central nervous system in mammals. γ-Amino-β-hydroxybutyric acid is a derivative of the neurotransmitter GABA. It has been claimed to be of value in neurological disorders and to have an antihypertensive effect. γ-Amino-β-hydroxybutyric acid can help overcome stress and anxiety, improve learning and boost memory function. It is also known to increase growth hormone levels, which help the body heal and rejuvenate itself. There are no reported side effects of γ-Amino-β-hydroxybutyric acid when taken at therapeutic dosages. At high dosages, some slight drowsiness may occur. Adverse effects have included dizziness and anorexia also.

CNS Activity

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
19.1 µM [EC50]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
GABOMADE
Primary
GABOMADE
Primary
GABOMADE

PubMed

Sample Use Guides

In Vivo Use Guide
Anxiety or stress: take 1 × 500mg tablet, or 2 × 250mg daily. For epilepsy take 2 × 500mg tablets twice daily.
Route of Administration: Oral
In Vitro Use Guide
Upon spinal ganglion cells, to which the GABOB is added in 0.5 mg/cc, is effective for maintenance and differentiation of nerve cells.