U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C15H21NO2
Molecular Weight 247.3327
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4-METHYLMETHYLPHENIDATE

SMILES

[H][C@]1(CCCCN1)[C@H](C(=O)OC)C2=CC=C(C)C=C2

InChI

InChIKey=WJZNCJIOIACDBR-UONOGXRCSA-N
InChI=1S/C15H21NO2/c1-11-6-8-12(9-7-11)14(15(17)18-2)13-5-3-4-10-16-13/h6-9,13-14,16H,3-5,10H2,1-2H3/t13-,14+/m0/s1

HIDE SMILES / InChI

Approval Year

Name Type Language
4-METHYLMETHYLPHENIDATE
Common Name English
2-PIPERIDINEACETIC ACID, .ALPHA.-(4-METHYLPHENYL)-, METHYL ESTER, (.ALPHA.R,2S)-REL-
Systematic Name English
4-ME-TMP
Common Name English
4-MMPH
Common Name English
THREO-4-METHYLMETHYLPHENIDATE
Common Name English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-4-Methylmethylphenidate
Created by admin on Thu Jul 06 16:09:59 UTC 2023 , Edited by admin on Thu Jul 06 16:09:59 UTC 2023
Code System Code Type Description
FDA UNII
1Y11XUO4EY
Created by admin on Thu Jul 06 16:09:59 UTC 2023 , Edited by admin on Thu Jul 06 16:09:59 UTC 2023
PRIMARY
CAS
191790-79-1
Created by admin on Thu Jul 06 16:09:59 UTC 2023 , Edited by admin on Thu Jul 06 16:09:59 UTC 2023
NON-SPECIFIC STEREOCHEMISTRY
WEB RESOURCE
4-MMPH
Created by admin on Thu Jul 06 16:09:59 UTC 2023 , Edited by admin on Thu Jul 06 16:09:59 UTC 2023
PRIMARY This appears to be the first new phenidate in the UK after the EPH, PPH, IPH, 3,4-CTMP and HDMP-28 ban. I've tried it a few times myself at 25-80mg oral, and from my experience it's the closest RC phenidate to Methylphenidate so far. Very similar duration, a little less potent.
CAS
467468-40-2
Created by admin on Thu Jul 06 16:09:59 UTC 2023 , Edited by admin on Thu Jul 06 16:09:59 UTC 2023
PRIMARY
EPA CompTox
DTXSID601029380
Created by admin on Thu Jul 06 16:09:59 UTC 2023 , Edited by admin on Thu Jul 06 16:09:59 UTC 2023
PRIMARY
WIKIPEDIA
4-Methylmethylphenidate
Created by admin on Thu Jul 06 16:09:59 UTC 2023 , Edited by admin on Thu Jul 06 16:09:59 UTC 2023
PRIMARY threo-4-Methylmethylphenidate (4-MeTMP) is a stimulant drug related to methylphenidate. It is slightly less potent than methylphenidate and has relatively low efficacy at blocking dopamine reuptake despite its high binding affinity, which led to its investigation as a possible substitute drug for treatment of stimulant abuse (cf. nocaine). On the other hand, several other simple ring-substituted derivatives of threo-methylphenidate such as the 4-fluoro and 3-chloro compounds are more potent than methylphenidate both in efficacy as dopamine reuptake inhibitors and in animal drug discrimination assays.
PUBCHEM
23815457
Created by admin on Thu Jul 06 16:09:59 UTC 2023 , Edited by admin on Thu Jul 06 16:09:59 UTC 2023
PRIMARY