PRALSETINIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H32FN9O2
Molecular Weight	533.6005
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PRALSETINIB

Structure Search

SMILES

CO[C@]1(CC[C@@H](CC1)C2=NC(NC3=NNC(C)=C3)=CC(C)=N2)C(=O)N[C@@H](C)C4=CC=C(N=C4)N5C=C(F)C=N5

InChI

InChIKey=GBLBJPZSROAGMF-BATDWUPUSA-N

InChI=1S/C27H32FN9O2/c1-16-11-22(33-23-12-17(2)35-36-23)34-25(31-16)19-7-9-27(39-4,10-8-19)26(38)32-18(3)20-5-6-24(29-13-20)37-15-21(28)14-30-37/h5-6,11-15,18-19H,7-10H2,1-4H3,(H,32,38)(H2,31,33,34,35,36)/t18-,19-,27-/m0/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

PRALSETINIB

Official Name

English

GAVRETO

Brand Name

English

(CIS)-N-((S)-1-(6-(4-FLUORO-1H-PYRAZOL-1-YL)PYRIDIN-3-YL)ETHYL)-1-METHOXY-4-(4-METHYL-6-(5-METHYL-1H-PYRAZOL-3-YLAMINO)PYRIMIDIN-2-YL)CYCLOHEXANECARBOXAMIDE

Systematic Name

English

CYCLOHEXANECARBOXAMIDE, N-((1S)-1-(6-(4-FLUORO-1H-PYRAZOL-1-YL)-3-PYRIDINYL)ETHYL)-1-METHOXY-4-(4-METHYL-6-((5-METHYL-1H-PYRAZOL-3-YL)AMINO)-2-PYRIMIDINYL)-, CIS-

Systematic Name

English

BLU-123244

Code

English

Pralsetinib [WHO-DD]

Common Name

English

X581238

Code

English

:PRALSETINIB [ORANGE BOOK]

Common Name

English

BLU123244

Code

English

pralsetinib [INN]

Common Name

English

X-581238

Code

English

PRALSETINIB [USAN]

Common Name

English

BLU-667

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

840321

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

FDA ORPHAN DRUG

634318

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

FDA ORPHAN DRUG

728519

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

Code System Code Type Description

CAS

2097132-94-8

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

PRIMARY

PUBCHEM

129073603

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

PRIMARY

NCI_THESAURUS

C132295

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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USAN

HI-27

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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RXCUI

2394936

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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EVMPD

SUB196574

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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INN

11004

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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SMS_ID

100000182481

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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EPA CompTox

DTXSID901336540

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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LACTMED

Pralsetinib

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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FDA UNII

1WPE73O1WV

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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DAILYMED

1WPE73O1WV

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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WIKIPEDIA

Pralsetinib

Created by admin on Sat Dec 16 13:23:00 GMT 2023 , Edited by admin on Sat Dec 16 13:23:00 GMT 2023

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ACTIVE MOIETY


					1WPE73O1WV