U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C27H32FN9O2
Molecular Weight 533.6005
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRALSETINIB

SMILES

CO[C@]1(CC[C@@H](CC1)C2=NC(NC3=NNC(C)=C3)=CC(C)=N2)C(=O)N[C@@H](C)C4=CC=C(N=C4)N5C=C(F)C=N5

InChI

InChIKey=GBLBJPZSROAGMF-BATDWUPUSA-N
InChI=1S/C27H32FN9O2/c1-16-11-22(33-23-12-17(2)35-36-23)34-25(31-16)19-7-9-27(39-4,10-8-19)26(38)32-18(3)20-5-6-24(29-13-20)37-15-21(28)14-30-37/h5-6,11-15,18-19H,7-10H2,1-4H3,(H,32,38)(H2,31,33,34,35,36)/t18-,19-,27-/m0/s1

HIDE SMILES / InChI

Approval Year

Name Type Language
PRALSETINIB
INN  
Official Name English
PRALSETINIB [WHO-DD]
Common Name English
(CIS)-N-((S)-1-(6-(4-FLUORO-1H-PYRAZOL-1-YL)PYRIDIN-3-YL)ETHYL)-1-METHOXY-4-(4-METHYL-6-(5-METHYL-1H-PYRAZOL-3-YLAMINO)PYRIMIDIN-2-YL)CYCLOHEXANECARBOXAMIDE
Systematic Name English
CYCLOHEXANECARBOXAMIDE, N-((1S)-1-(6-(4-FLUORO-1H-PYRAZOL-1-YL)-3-PYRIDINYL)ETHYL)-1-METHOXY-4-(4-METHYL-6-((5-METHYL-1H-PYRAZOL-3-YL)AMINO)-2-PYRIMIDINYL)-, CIS-
Systematic Name English
PRALSETINIB [INN]
Common Name English
BLU-667
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 634318
Created by admin on Mon Oct 21 20:13:08 UTC 2019 , Edited by admin on Mon Oct 21 20:13:08 UTC 2019
Code System Code Type Description
CAS
2097132-94-8
Created by admin on Mon Oct 21 20:13:08 UTC 2019 , Edited by admin on Mon Oct 21 20:13:08 UTC 2019
PRIMARY
PUBCHEM
129073603
Created by admin on Mon Oct 21 20:13:08 UTC 2019 , Edited by admin on Mon Oct 21 20:13:08 UTC 2019
PRIMARY
EVMPD
SUB196574
Created by admin on Mon Oct 21 20:13:08 UTC 2019 , Edited by admin on Mon Oct 21 20:13:08 UTC 2019
PRIMARY
INN
11004
Created by admin on Mon Oct 21 20:13:08 UTC 2019 , Edited by admin on Mon Oct 21 20:13:08 UTC 2019
PRIMARY